Deep brain stimulation (DBS) of the subcallosal cingulate (SCC) can provide long-term symptom relief for treatment-resistant depression (TRD). However, achieving stable recovery is unpredictable, typically requiring trial-and-error stimulation adjustments due to individual recovery trajectories and subjective symptom reporting. We currently lack objective brain-based biomarkers to guide clinical decisions by distinguishing natural transient mood fluctuations from situations requiring intervention.
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April 2023
A brain-computer interface (BCI) is a system that allows a human operator to use only mental commands in controlling end effectors that interact with the world around them. Such a system consists of a measurement device to record the human user's brain activity, which is then processed into commands that drive a system end effector. BCIs involve either invasive measurements which allow for high-complexity control but are generally infeasible, or noninvasive measurements which offer lower quality signals but are more practical to use.
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