Publications by authors named "Gregory C Strohmeyer"

Background: A distal tibia osteochondral allograft is a potential graft option for glenoid reconstruction because the distal tibia may have a similar radius of curvature (ROC) as the glenoid. This study evaluated ROC mismatch as measured on computed tomography (CT) scans between the glenoid, distal tibia, and humeral head.

Methods: Bilateral CT images were formatted for 10 decedents from the Office of the Medical Investigator database, giving 20 specimens per anatomic location.

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Lectins are invaluable tools for chemical biology because they recognize carbohydrate arrays. Multivalent carbohydrate binding by lectins is important for processes such as bacterial and viral adhesion and cancer metastasis. A better understanding of mammalian lectin binding to carbohydrate arrays is critical for controlling these and other cellular recognition processes.

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Article Synopsis
  • Functionalized G(3) and G(4)-PAMAM dendrimers were synthesized and characterized using MALDI-TOF MS and NMR spectroscopy.
  • Precipitation assays were conducted to evaluate the interaction of these dimannose-functionalized dendrimers with Cyanovirin-N, a protein that inhibits HIV by preventing virus-to-cell fusion.
  • The study focuses on the potential of these dendrimers to enhance the effectiveness of HIV treatments through their binding properties.
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