Sacubitril-valsartan in heart failure and multimorbidity patients.

Aims: The poor control of symptoms in patients with advanced heart failure with reduced ejection function (HFrEF) can limit the functionality of patients. Sacubitril-valsartan, compared with enalapril, has been shown to reduce mortality and hospitalization, and nowadays, there is still little evidence about the improvement on functionality. The aim of our study is to analyse the improvement of the functional class and the 6 min walking test (6MWT) in patients with multiple pathologies and advanced heart failure.

Factors associated to institutionalization and mortality over three years, in elderly people with a hip fracture-An observational study.

Objective: To identify the factors associated to institutionalization and mortality in elderly patients with hip fractures (HF).

Design: Thirty-six months observational study.

Setting: A post-acute rehabilitation ward.

[Control of cardiovascular risk factors in patients with stroke attended in primary care in Spain. ICTUSCARE study].

Background: The aim of this cross-sectional, multicenter survey was: 1) To investigate the level of control of cardiovascuar risk factors in patients with a previous stroke. 2) To know the pharmacological therapy used to attain the control.

Patients And Methods: Data obtained from a total of 955 patients were included in the analysis.

[Seroprevalence of Lyme disease in Navarra, Spain].

Background And Objective: To establish the seroprevalence of infection by Borrelia burgdorferi in Navarre (Spain).

Patients And Method: Serum samples of 1,429 individuals considered representative of the population of Navarre were analyzed. The individuals were recruited from a list issued by the government of Navarre.

[Pneumonia in the elderly. Factors related with the mortality during the episode and after the discharge].

Background And Objective: Pneumonia in the elderly (PIE) is a growing disease that causes great morbidity and mortality with frequent admissions to hospital and increasing health costs. The objective of our study was yo analyze the characteristics of PIE in an internal medicine hospital ward, the influence of quality of life (Katz index and scale of Karnofsky) on its evolution and after the discharge and the factors of poor prognosis during the episode of PIE and throughout the ambulatory follow-up.

Patients And Method: All the patients suffering from PIE admitted to the internal medicine ward of our hospital during a two years period were included in the study (125).