Fractionated Ocimum gratissimum leaf extract inhibit prostate cancer (PC3·AR) cells growth by reducing androgen receptor and survivin levels.

In this study, the antiproliferative activity of the organic solvent-soluble and aqueous extracts of Ocimum gratissimum leaf against the prostate cancer cells PC3·AR were evaluated by their inhibitory effects on the Androgen Receptor (AR) and Survivin protein. Two organic solvent-soluble extracts P2 and P3-2, and a water- soluble extract, PS/PT1, were found to reduce AR and Survivin levels in a time-dependent manner. In addition, extract PS/PT1, also exhibited the inhibitory activity in a dose-dependent manner.

Selected morphological characteristics, lead uptake and phytochelatin synthesis by coffeeweed (Sesbania exaltata Raf.) grown in elevated levels of lead-contaminated soil.

Remediation of lead-contaminated soil is significant due to the inherent toxicity of lead (Pb), and the quantity of Pb discharged into the soil. One of the most cost-effective and environmentally sound technologies for the cleanup of metal-contaminated soils is through the use of plants. While much is known about the ecological evolution of metal tolerance in plants, the physiological, biochemical, and genetic mechanisms of tolerance is not well understood in the majority of resistant ecotypes such as the legume, Sesbania exaltata Raf.

Identification of drought-responsive universal stress proteins in viridiplantae.

Genes encoding proteins that contain the universal stress protein (USP) domain are known to provide bacteria, archaea, fungi, protozoa, and plants with the ability to respond to a plethora of environmental stresses. Specifically in plants, drought tolerance is a desirable phenotype. However, limited focused and organized functional genomic datasets exist on drought-responsive plant USP genes to facilitate their characterization.

Potential cancer-fighting Ocimum gratissimum (OG) leaf extracts: increased anti-proliferation activity of partially purified fractions and their spectral fingerprints.

Introduction: Cancer causes about 13% of all deaths. According to the American Cancer Society, world-wide cancer deaths were 7.6 million in 2007.

Bioavailability and uptake of lead by coffeeweed (Sesbania exaltata Raf.).

Lead (Pb) is recognized as one of the most pervasive environmental health concerns in the industrialized world. While there has been a substantial reduction in the use of Pb in gasoline, water pipes, and Pb-based residential paint, residual Pb from their use is still in the environment and constitutes an important source of Pb in the atmosphere, water, and soil. Soil acts as a sink for these anthropogenic sources of Pb, accumulating the deposits over time in the upper 2 - 5 cm of undisturbed soil.

Assessment of the efficacy of chelate-assisted phytoextraction of lead by coffeeweed (Sesbania exaltata Raf.).

Lead (Pb), depending upon the reactant surface, pH, redox potential and other factors can bind tightly to the soil with a retention time of many centuries. Soil-metal interactions by sorption, precipitation and complexation processes, and differences between plant species in metal uptake efficiency, transport, and susceptibility make a general prediction of soil metal bioavailability and risks of plant metal toxicity difficult. Moreover, the tight binding characteristic of Pb to soils and plant materials make a significant portion of Pb unavailable for uptake by plants.

Morphological and physiological responses of morning glory (Ipomoea lacunosa L.) grown in a lead- and chelate-amended soil.

Lead (Pb) is one of the most toxic metals in the environment and may cause drastic morphological and physiological deformities in Ipomoea lacunosa. The goal of this research was to evaluate some morphological and physiological responses of morning glory grown on a Pb- and chelate-amended soil. Soil samples were analyzed, at Mississippi State University Soil Laboratory, for physico-chemical parameters, such as soil texture (73% sand, 23% silt, 4.

Heavy metal uptake, translocation, and bioaccumulation studies of Triticum aestivum cultivated in contaminated dredged materials.

Phytoremediation is a technology that uses vegetation to remediate contaminants from water, soil, and sediments. Unlike traditional remediation techniques such as soil washing or vitrification, phytoremediation offers a technology that is solar-driven, aesthetically pleasing, and cost effective. Recent studies indicate that winter wheat (Triticum aestivum L.