Blood-based protein biomarkers and red blood cell aggregation in pancreatic cancer.

Background: Pancreatic ductal adenocarcinoma (PDAC) is highly malignant with a low 5-year survival rate. Blood biomarkers may be of value for the noninvasive diagnosis of pancreatic cancer.

Objective: This study assessed blood-based biomarkers and disturbances in red blood cell aggregation associated with pancreatic cancer.

The relationship between the rheological behavior of RBCs and angiogenesis in the morbidly obese.

Objective: The aim of this study was to investigate the relationship between red blood cell (RBC) aggregation and deformability and angiogenesis parameters in obese patients.

Methods: We studied 35 obese subjects and 20 non-obese people as a control group. Angiogenesis was detected using Bio-Plex Pro Human Angiogenesis Multiplex Assays.