Intraperitoneal drug delivery systems releasing cytostatic agents to target gastro-intestinal peritoneal metastases in laboratory animals: a systematic review.

For peritoneal metastases (PM), there are few curative treatment options, and they are only available for a select patient group. Recently, new therapies have been developed to deliver intraperitoneal chemotherapy for a prolonged period, suitable for a larger patient group. These drug delivery systems (DDSs) seem promising in the experimental setting.

Sedentary behaviour, physical activity and cardiometabolic health in highly trained athletes: A systematic review and meta-analysis.

Prolonged periods of sedentary time appear to increase the risk for the development of several chronic conditions and all-cause mortality, even when moderate-to-vigorous physical activity (MVPA) is taken into consideration. However, whether the beneficial health effects of MVPA in highly active individuals remain present when leisure time is spent sedentary remains speculative. Therefore, we systematically evaluated off-training sedentary behaviour and physical activity levels in athletes.

Can consumer wearable activity tracker-based interventions improve physical activity and cardiometabolic health in patients with chronic diseases? A systematic review and meta-analysis of randomised controlled trials.

Background: To date, it is unclear if consumer wearable activity trackers (CWATs), with or without behaviour multi-component strategies, effectively improve adherence to physical activity and health outcomes under free living conditions in populations with chronic diseases. Therefore, we systematically evaluated the efficacy of CWAT-based interventions to promote physical activity levels and cardiometabolic health in populations with chronic diseases.

Methods: Randomised controlled trials were collected from five bibliographic databases (PubMed, Embase, Web of Science, The Cochrane Central Register of Controlled Trials and CINAHL).