Publications by authors named "Gregoire Saltiel"
Article Synopsis
- Cytomegalovirus (CMV) is a major concern for individuals who have undergone solid organ transplants, with letermovir emerging as a less toxic alternative for CMV prevention, particularly in heart transplant recipients.
- In a study involving 10 heart transplant patients, letermovir was effective at preventing CMV infections during use, although some patients experienced breakthrough infections after stopping the drug.
- While letermovir showed minimal side effects and required dosage adjustments for certain immunosuppressants, further monitoring and research are necessary to assess long-term efficacy and safety.
Prosthetic Joint Infections: Is Rifampicin-Combination Therapy Beneficial?
Antibiotics (Basel)
December 2022
No consensus has been reached on the optimal antibiotic regimen to treat PJIs (Ca-PJIs). In vitro studies showed excellent rifampicin efficacy against biofilm-associated infections, but clinical studies did not confirm the superiority of rifampicin-combined therapy over monotherapy. This prospective cohort study was undertaken to analyze the outcomes of 70 patients who underwent exchange arthroplasty for chronic monomicrobial Ca-PJI and were treated with rifampicin or without between 2004 and 2019.
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