Publications by authors named "Gregoire Le Gac"

Article Synopsis
  • A multicentric study analyzed the prevalence and risk factors of persistent pain in patients who stayed in an ICU for 48 hours or more, revealing that 47.7% experienced significant pain three months post-admission.
  • Key risk factors for persistent pain included being female, previous use of antidepressants, specific positioning during care, and having pain symptoms at discharge.
  • Despite the high prevalence of pain, only 11.3% of patients received specialized pain management within three months, indicating a need for better pain management strategies in critical care settings.
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Background: Hepatocellular carcinoma (HCC) is an aggressive cancer with limited therapeutic options. Retrospective studies have shown that the administration of local anesthetics (LAs) during cancer surgery could reduce cancer recurrence. Besides, experimental studies reported that LAs could inhibit the growth of cancer cells.

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Purpose: Frailty is a recent concept used for evaluating elderly individuals. Our study determined the prevalence of frailty in intensive care unit (ICU) patients and its impact on the rate of mortality.

Methods: A multicenter, prospective, observational study performed in four ICUs in France included 196 patients aged ≥65 years hospitalized for >24 h during a 6-month study period.

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