Publications by authors named "Greg Stefanou"
Background: Debate continues regarding the benefits versus risks of initial resection of the primary tumor in metastatic colorectal cancer (mCRC) patients with an asymptomatic primary tumor. Although the benefit of the anti-vascular endothelial growth factor agent bevacizumab alongside first-line chemotherapy in mCRC is established, the impact of bevacizumab on the intact primary tumor (IPT) is less well understood.
Methods: Data from an Australian mCRC registry were used to assess the impact of bevacizumab-based regimens in the presence of an IPT, to see if this differs from effects in resected primary tumor (RPT) patients and to understand the safety profile of bevacizumab in patients with IPT.
Background: Treatments for oesophageal cancers have historically been surgical, and surgical treatment remains the mainstay of treatment for localised oesophageal carcinoma (stage I-III). For stage IV disease, systemic chemotherapy is the mainstay of treatment.
Objective: This article provides an overview of curative and palliative management options for oesophageal carcinoma.