Dimple on the shoulder after a ski injury.

Clinical Introduction: A 74-year-old woman was brought to the ski clinic shortly after a fall on her left shoulder while skiing. She did not remember the exact fall mechanism. She felt a popping sensation in her left shoulder and was unable to move her left arm due to severe pain.

Management of mild-to-moderate osteoarthritis: a study of the primary care perspective.

Objectives: Examine the knowledge, attitudes, and practice patterns of primary care clinicians regarding the management of mild-to-moderate osteoarthritis (OA).

Design: Case vignette-based survey.

Methods: A survey was distributed to 251 physicians, physician assistants (PAs), and nurse practitioners (NPs) in the primary care setting.

Sports-related injuries in the United States: who gets care and who does not.

Objective: To describe the pattern of sports-related injuries (SRIs), healthcare obtained for these injuries, and factors associated with obtaining healthcare.

Design And Setting: Retrospective analysis of the adult subgroup within the Medical Expenditures Panel Survey dataset from 1996 to 2001, which is weighted to represent all noninstitutionalized US residents.

Participants: Survey participants (2996) aged 0 to 64 years reporting an SRI.

Systemic correction of a fatty acid oxidation defect by intramuscular injection of a recombinant adeno-associated virus vector.

Mitochondrial beta-oxidation of fatty acids is required to meet physiologic energy requirements during illness and periods of fasting or physiologic stress, and is most active in liver and striated muscle. Acyl-CoA dehydrogenases of varying chain-length specificities represent the first step in the mitochondria for each round of beta-oxidation, each of which removes two-carbon units as acetyl-CoA for entry into the tricarboxylic acid cycle. We have used recombinant adeno-associated virus (rAAV) vectors expressing short-chain acyl-CoA dehydrogenase (SCAD) to correct the accumulation of fatty acyl-CoA intermediates in deficient cell lines.

Solar Injury and Heat Illness.

In brief Children are particularly susceptible to solar injury to the skin and eyes and to heat illness-heat cramps, heat exhaustion, and heatstroke. Because sunburn during childhood is linked to subsequent skin cancer, aggressive prevention through use of sunscreens and other protective measures is critical. Physicians should screen for risk factors for heat illness, such as hypohydration, obesity, poor conditioning, and certain illnesses.