Correction to: Physiological resolution of periodic breath holding during heavy-intensity Fartlek exercise.

The original version of this article unfortunately contained a mistake.

Physiological resolution of periodic breath holding during heavy-intensity Fartlek exercise.

Purpose: The purpose was to compare the singular and combined effects of 5 s breath holds (BH) and 5 s sprints, every 30 s, during continuous high-intensity exercise, on ventilation ([Formula: see text]), oxygen uptake ([Formula: see text]O) and associated kinetics (τ), carbon dioxide production ([Formula: see text]CO), and arterialized-capillary lactate concentration ([La]).

Methods: Ten men (24 ± 3 years) performed 4-6 min ergometer protocols that included a step-transition from 20 W to a power output of 50% of the difference between lactate threshold and [Formula: see text]O peak (Δ50%) including: (1) a continuous protocol (CONT) with free breathing, (2) an intermittent BH protocol (CONT-BH); repeated cycles of 5 s BH: 25 s free breathing, (3) a Fartlek protocol (Fartlek); repeated 5 s at peak aerobic power output: 25 s at Δ50%; (4) combining the 5 s Fartlek and CONT-BH protocol (Fartlek-BH). Breath-by-breath gas exchange, measured by mass spectrometry and turbine, was recorded.

The influence on sarcopenia of muscle quality and quantity derived from magnetic resonance imaging and neuromuscular properties.

The relative contributions of intrinsic and extrinsic neuromuscular factors on sarcopenia are poorly understood. The associations among age-related declines of strength, muscle mass, and muscle quality in response to motor unit (MU) loss have not been systematically investigated in the same groups of subjects. The purpose was to assess MU loss, MRI-derived muscle cross-sectional area (CSA), muscle protein quantity (MPQ), and normalized strength of the dorsiflexors in one group of young (~25 years) adult males compared with two groups of healthy men aged 60–85 years.

Differential Age-related Changes in Bone Geometry between the Humerus and the Femur in Healthy Men.

Muscle pull and weight-bearing are key mechanical determinants of bone geometry which is an important feature of bone strength that declines with adult aging. However, the relative importance of these determinants in young and old adults has not been evaluated systematically. To differentiate the influence of each type of mechanical loading we compared humeral and femoral bone shaft geometry and cross-sectional area (CSA) of the arm and thigh muscles in young and old men.

Differences in leg bone geometry in young, old and very old women.

Bone geometry is an important measure of bone strength and is known to be affected by weight-bearing and adult ageing. Engagement in weight-bearing activity decreases with age, thus in this study we compared bone geometry changes between weight-bearing (tibia) and non-weight-bearing (fibula) leg bones in three different age groups of women. Magnetic resonance images of the right leg were acquired in 9 young (20-27 years), 7 old (61-69 years) and 7 very old (71-80 years) women.

Effects of ammonium chloride ingestion on phosphocreatine metabolism during moderate- and heavy-intensity plantar-flexion exercise.

This study examined the effects of NH(4)Cl ingestion on phosphocreatine (PCr) metabolism during 9 min of moderate- (MOD) and heavy- (HVY) intensity constant-load isotonic plantar-flexion exercise. Healthy young adult male subjects (n = 8) completed both a control (CON) and NH(4)Cl ingestion (ACID) trial. Phosphorus-31 magnetic resonance spectroscopy was used to monitor changes in intracellular pH (pHi), [Pi], [PCr], and [ATP].

Geometry of a weight-bearing and non-weight-bearing bone in the legs of young, old, and very old men.

Bone geometry is an important determinant of bone strength and is influenced by muscle pull and weight-bearing. Muscle mass and exposure to weight-bearing decrease with age and thus the purpose of the study was to compare bone geometry of the weight-bearing (tibia) and non-weight-bearing (fibula) bones of the leg in different age groups. Magnetic resonance images of the right leg were acquired in 13 young (26 yr), 13 old (66 yr), and 13 very old men (83 yr).

Muscle metabolism and acid-base status during exercise in forearm work-related myalgia measured with 31P-MRS.

In this study, we examined muscle metabolic and acid-base status during incremental wrist extension exercise in the forearm of individuals with work-related myalgia (WRM). Eighteen women employed in full-time occupations involving repetitive forearm labor were recruited in this cross-sectional study. Nine of these women were diagnosed with WRM, while the other nine had no previous WRM history and were used as age-matched controls (Con).

Prior exercise delays the onset of acidosis during incremental exercise.

The effects of prior moderate- and prior heavy-intensity exercise on the subsequent metabolic response to incremental exercise were examined. Healthy, young adult subjects (n = 8) performed three randomized plantar-flexion exercise tests: 1) an incremental exercise test (approximately 0.6 W/min) to volitional fatigue (Ramp); 2) Ramp preceded by 6 min of moderate-intensity, constant-load exercise below the intracellular pH threshold (pHT; Mod-Ramp); and 3) Ramp preceded by 6 min of heavy-intensity, constant-load exercise above pHT (Hvy-Ramp); the constant-load and incremental exercise periods were separated by 6 min of rest.

Characteristics of a MR-compatible ankle exercise ergometer for a 3.0 T head-only MR scanner.

An exercise ergometer, for isometric or dynamic contraction of both dorsiflexion and/or plantarflexion exercise, was designed and constructed for a 3.0 T head-only MR scanner. The principal features of this MR-compatible ergometer include electronic devices for quantification of force (during isometric exercise) and angular displacement (during dynamic exercise), without any significant losses to external motions or frictions.

Effects of maximal isometric and isokinetic resistance training on strength and functional mobility in older adults.

Background: The aim of the present study was to compare the changes in voluntary strength (isometric, concentric, and eccentric) and functional mobility in response to maximal isokinetic eccentric-only resistance training to those elicited by maximal isometric-only or maximal isokinetic concentric-only resistance training in older adults.

Methods: Twelve women (73 +/- 7 years) and 18 men (73 +/- 5 years) completed a 12-week training program (three times per week) using a Biodex System 3 dynamometer. Primary outcome measures included peak isometric and isokinetic (concentric and eccentric) knee extensor strength, concentric work, concentric power, stair ascent and descent, and gait speed.

Reliability of isokinetic and isometric knee-extensor force in older women.

Because of the need for efficient, consistent strength measurements, the test-retest reliability of concentric, isometric, and eccentric strength; concentric work; and concentric power was determined in older women without a familiarization session. The reliability of measures derived from a single peak score were compared with those derived from an averaged score. On 2 occasions 25 older women with a mean age of 72 +/- 6 years performed 3 submaximal knee extensions and 5 maximal contractions on an isokinetic dynamometer at 90 degrees/s (CON), 0 degrees/s, and -90 degrees/s on both lower limbs.

Reliability of a single-session isokinetic and isometric strength measurement protocol in older men.

Background: The purposes of the current study were (a) to determine the test-retest reliability of a single-session isokinetic and isometric strength testing protocol in older healthy men, and (b) to compare the outcomes of the reliability measures derived from averaged torque scores with those derived from a single peak torque score.

Methods: In 19 men (mean age, 72 +/- 5 years), both lower limbs were assessed independently on 2 separate test days using the Biodex System 3 dynamometer. After completing a 5-minute warm-up, each man performed three submaximal knee extensions followed by five maximal contractions at 90 degrees /s (CON), 0 degrees /s (ISO), and -90 degrees /s (ECC).

Metabolic effects of induced alkalosis during progressive forearm exercise to fatigue.

Metabolic alkalosis induced by sodium bicarbonate (NaHCO(3)) ingestion has been shown to enhance performance during brief high-intensity exercise. The mechanisms associated with this increase in performance may include increased muscle phosphocreatine (PCr) breakdown, muscle glycogen utilization, and plasma lactate (Lac(-)(pl)) accumulation. Together, these changes would imply a shift toward a greater contribution of anaerobic energy production, but this statement has been subject to debate.

Muscle fiber number in the biceps brachii muscle of young and old men.

We have compared the number of muscle fibers in the biceps brachii muscle (BB) of six old men (82.3 +/- 4.3 years) and six young men (21.

Changes in human muscle transverse relaxation following short-term creatine supplementation.

The rapid increase in body mass that often occurs following creatine (Cr) supplementation is believed to be due to intracellular water retention. The purpose of this study was to determine whether Cr consumption alters the magnetic resonance (MR) transverse relaxation (T(2)) distribution of skeletal muscle. Transverse relaxation can be used to model water compartments within a cell or tissue.