Publications by authors named "Greg D Ferguson"
Am J Pathol
November 2024
Article Synopsis
- Regulatory T (Treg) cells are crucial for preventing early pregnancy loss, and boosting these cells may improve reproductive success in problematic cases.
- A study using an abortion-prone mouse model showed that administering a specific IL-2 treatment (IL-2/JES6-1) significantly increased the number of beneficial Treg cells in the uterus, leading to improved fetal outcomes.
- Although the treatment reduced the rate of fetal loss from 31% to 10%, it also resulted in a slight decrease in fetal weight during late gestation, indicating potential trade-offs that need further exploration.
