Estimation of In Vivo Human Carotid Artery Elasticity Using Arterial Dispersion Ultrasound Vibrometry.

Objective: Arterial stiffening serves as an early indicator for a variety of cardiovascular diseases. Arterial Dispersion Ultrasound Vibrometry (ADUV) is a method that leverages acoustic radiation force to stimulate arterial wall motion, assess wave propagation characteristics, and subsequently calculate the arterial shear modulus. Previously, we introduced an inversion technique based on a guided cylindrical wave model, which proved effective in rubber tube phantom experiments.

Attenuation Measuring Ultrasound Shearwave Elastography (AMUSE) as Noninvasive Imaging Biomarker for Liver Acute Cellular Rejection.

Objective: There are over 9000 liver transplants in the United States per year, with acute cellular rejection (ACR) being a prevalent early post-transplant complication (20%-40%) treated using corticosteroids. Ischemia-reperfusion injury (IRI), another early post-transplant pathology, has similar laboratory results but typically resolves without therapy. ACR confirmation requires invasive liver biopsy, bearing risks like hemorrhage and pneumothorax.

Arthropods Associated with Invasive (Rosales: Rhamnaceae): Implications for Invasive Plant and Insect Management.

The invasive shrub glossy buckthorn () has been progressively colonizing the Northeastern United States and Southeastern Canada for more than a century. To determine the dominant arthropod orders and species associated with , field surveys were conducted for two years across 16 plots within the Allegheny National Forest, Pennsylvania, USA. Statistical analyses were employed to assess the impact of seasonal variation on insect order richness and diversity.

Spatial Patterns of (Rosales: Rhamnaceae): Implications for Invasive Plant Management.

Glossy buckthorn () (Rosales: Rhamnaceae) is an invasive shrub from Europe that has been invading North America for over a century and threatening native vegetation in open and disturbed habitats. The treatment of is currently restricted to the roadside, suggesting any individual residing within the forest would be left unmanaged and would continue to spread in the area. This research was conducted to determine the spatial patterns and relationship of with forest roads.

Non-invasive Measurement of the Viscoelasticity of the Optic Nerve and Sclera for Assessing Papilledema: A Pilot Clinical Study.

Objective: The purpose of this study was to evaluate our novel ultrasound vibro-elastography (UVE) technique for assessing patients with papilledema by non-invasively measuring shear wave speed (SWS), elasticity and viscosity properties of the optic nerve and sclera.

Methods: Shear wave speeds were measured at three frequencies-100, 150 and 200 Hz-on the optic nerve and sclera tissues for assessing patients with papilledema resulting from idiopathic intracranial hypertension (IIH). The method was evaluated in six papilledema patients and six controls on two separate locations for each participant (i.

Comb Detection for Measuring Shear Wave Propagation.

Plane wave compounding (PWC) is widely used to measure the propagation of shear waves. Implementing PWC on most commercial ultrasound scanners is challenging because all channel (>128) data must be processed or transferred to the host computing unit in real time. Comb detection transmits multiple focused beams simultaneously and results in a reduced number of receive lines to be processed in parallel.

Precision Detection and Assessment of Ash Death and Decline Caused by the Emerald Ash Borer Using Drones and Deep Learning.

Emerald ash borer () is an invasive pest that has killed millions of ash trees ( spp.) in the USA since its first detection in 2002. Although the current methods for trapping emerald ash borers (e.

Ultrasonographic Detection and Surgical Retrieval of a Nonmetallic Twinkle Marker in Breast Cancer: Pilot Study.

Purpose To evaluate the short-term safety of a nonmetallic twinkle marker and compare its conspicuity at color Doppler US with that of standard breast biopsy clips and radioactive seeds by using B-mode US in axillary lymph nodes. Materials and Methods This prospective study (November 2020-July 2021) of participants with node-positive breast cancer who completed chemotherapy involved placing a twinkle marker at the time of preoperative radioactive seed localization. A five-point scoring system (1 = easiest, 5 = most difficult) was used to rate the ease of identifying the clip, seed, and twinkle marker on postlocalization sonograms, mammograms, specimen radiographs, and gross pathologic specimens.

Measurement of wave propagation through a tube using dual transducers for elastography in arteries.

Measuring waves induced with acoustic radiation force (ARF) in arteries has been studied over the last decade. To date, it remains a challenge to quantitatively assess the local arterial biomechanical properties. The cylindrical shape and waveguide behavior of waves propagating in the arterial wall pose complexities to determining the mechanical properties of the artery.

Twinkling-guided ultrasound detection of polymethyl methacrylate as a potential breast biopsy marker: a comparative investigation.

Since its first description 25 years ago, color Doppler twinkling has been a compelling ultrasound feature in diagnosing urinary stones. While the fundamental cause of twinkling remains elusive, the distinctive twinkling signature is diagnostically valuable in clinical practice. It can be inferred that if an entity twinkles, it empirically has certain physical features.

The influence of acoustic radiation force beam shape and location on wave spectral content for arterial dispersion ultrasound vibrometry.

. Arterial dispersion ultrasound vibrometry (ADUV) relies on the use of guided waves in arterial geometries for shear wave elastography measurements. Both the generation of waves through the use of acoustic radiation force (ARF) and the techniques employed to infer the speed of the resulting wave motion affect the spectral content and accuracy of the measurement.

A New Plane Wave Compounding Scheme Using Phase Compensation for Motion Detection.

Plane wave (PW) transmission has enabled multiple new applications, such as shear wave elastography, ultrafast Doppler imaging, and functional ultrasound imaging. PW compounding (PWC), which coherently sums the echo signals from multiple PW transmits with different angles, is widely used to improve B-mode image quality. When the motion between two speckle images is estimated, PWC suffers from an inherent displacement estimation error.

Toward improved accuracy in shear wave elastography of arteries through controlling the arterial response to ultrasound perturbation in-silico and in phantoms.

Dispersion-based inversion has been proposed as a viable direction for materials characterization of arteries, allowing clinicians to better study cardiovascular conditions using shear wave elastography. However, these methods rely onknowledge of the vibrational modes dominating the propagating waves induced by acoustic radiation force excitation: differences between anticipated and real modal content are known to yield errors in the inversion. We seek to improve the accuracy of this process by modeling the artery as a fluid-immersed cylindrical waveguide and building an analytical framework to prescribe radiation force excitations that will selectively excite certain waveguide modes using ultrasound acoustic radiation force.

Using Ultrasound Color Doppler Twinkling to Identify Biopsy Markers in the Breast and Axilla.

In breast radiology, ultrasound detection of biopsy markers or clips for localization purposes is often challenging, especially in the axilla. The purpose of this research was to test the hypothesis that the surface roughness of biopsy clips would elicit a twinkling signature on color Doppler, making them more readily identifiable by ultrasound. Ultrasound color Doppler imaging of 12 biopsy markers was performed and consensus scoring of the degree of twinkling (0 [no twinkling] to 4 [exuberant twinkling]) was obtained for each of the markers.

Multimodal guided wave inversion for arterial stiffness: methodology and validation in phantoms.

Arterial stiffness is an important biomarker for many cardiovascular diseases. Shear wave elastography is a recent technique aimed at estimating local arterial stiffness using guided wave inversion (GWI), i.e.

Time-Aligned Plane Wave Compounding Methods for High-Frame-Rate Shear Wave Elastography: Experimental Validation and Performance Assessment on Tissue Phantoms.

Shear wave elastography (SWE) is an ultrasonic technique able to quantitatively assess the mechanical properties of tissues by combining acoustic radiation force and ultrafast imaging. While utilizing coherent plane wave compounding enhances echo and shear wave motion signal-to-noise ratio (SNR), it also reduces the effective pulse repetition frequency (PRF), affecting the accuracy of the measurements of motion and, consequently, of material properties. It is important to maintain both high-motion SNR and PRF, particularly for the characterization of (material and/or geometrical) dispersive tissues such as arteries.

Three-dimensional shear wave elastography on conventional ultrasound scanners with external vibration.

Two-dimensional (2D) ultrasound shear wave elastography (SWE) has been widely used for soft tissue properties assessment. Given that shear waves propagate in three dimensions (3D), extending SWE from 2D to 3D is important for comprehensive and accurate stiffness measurement. However, implementation of 3D SWE on a conventional ultrasound scanner is challenging due to the low volume rate (tens of Hertz) associated with limited parallel receive capability of the scanner's hardware beamformer.

Injury Surveillance and Evaluation of Medical Services Utilized During the 2016 Track and Field Olympic Trials.

Background: Injury surveillance systems have been implemented at world championships, yet no previous work has determined the burden of injuries during the United States Track and Field Olympic Trials. Additionally, the type of medical service providers utilized throughout the meet has not been reported, leaving it unclear whether optimal staffing needs are being met.

Purpose: To describe the incidence of injuries presenting to the medical team at the 2016 US Track and Field Olympic Trials (Eugene, Oregon) by event type and competitor demographics.

Open- and Closed-chest Measurements of Left-Ventricular Myocardial Viscoelasticity using Lamb wave Dispersion Ultrasound Vibrometry (LDUV): A Feasibility Study.

Diastolic dysfunction causes close to half of congestive heart failures and is associated with increased stiffness in left-ventricular myocardium. A clinical tool capable of measuring viscoelasticity of the myocardium could be beneficial in clinical settings. We used Lamb wave Dispersion Ultrasound Vibrometry (LDUV) for assessing the feasibility of making non-invasive measurements of myocardial elasticity and viscosity in pigs.

Probe Oscillation Shear Wave Elastography: Initial In Vivo Results in Liver.

Shear wave elastography methods are able to accurately measure tissue stiffness, allowing these techniques to monitor the progression of hepatic fibrosis. While many methods rely on acoustic radiation force to generate shear waves for 2-D imaging, probe oscillation shear wave elastography (PROSE) provides an alternative approach by generating shear waves through continuous vibration of the ultrasound probe while simultaneously detecting the resulting motion. The generated shear wave field in in vivo liver is complicated, and the amplitude and quality of these shear waves can be influenced by the placement of the vibrating probe.

Application of Acoustoelasticity to Evaluate Nonlinear Modulus in Ex Vivo Kidneys.

Currently, dynamic elastography techniques estimate the linear elastic shear modulus of different body tissues. New methods that investigate other properties of soft tissues such as anisotropy, viscosity, and shear nonlinearity would provide more information about the structure and function of the tissue and might provide a better contrast than tissue stiffness and hence provide more effective diagnostic tools for some diseases. It has previously been shown that shear wave velocity in a medium changes due to an applied stress, a phenomenon called acoustoelasticity (AE).