Inclusion Complex between Local Anesthetic/2-hydroxypropyl-β-cyclodextrin in Stealth Liposome.

The drugs delivery system in the treatment of diseases has advantages such as reduced toxicity, increased availability of the drug, etc. Therefore, studies of the supramolecular interactions between local anesthetics (LAs) butamben (BTB) or ropivacaine (RVC) complexed with 2-hydroxypropyl-β-cyclodextrin (HP-βCD) and carried in Stealth liposomal (SL) are performed. H-NMR nuclear magnetic resonance (DOSY and STD) were used as the main tools.

Antiproliferative activity and energy calculations of a new triterpene isolated from the palm tree .

Mart () is a palm tree native to South America, widely studied for biodiesel production. The aim of this work was to perform the first phytochemical study of leaves, as well as to do biological assays against human cancer cell lines. A new triterpene of the hopane class named totaiol three known triterpenes , and two phytosteroids were identified.

The ability of farnesol to prevent adhesion and disrupt Fusarium keratoplasticum biofilm.

A biofilm is represented by a community of microorganisms capable of adhering to a surface and producing substances that envelop the cells, forming an extracellular matrix. The extracellular matrix is responsible for protecting microorganisms against environmental stress, hosts the immune system and confers resistance to antimicrobials. Fusarium keratoplasticum is a common species of FSSC (Fusarium solani species complex) associated with human infections, being the most prevalent species related to biofilm formation in hospital water systems and internal pipelines.