Uncovering the Risks and Benefits of Patent Foramen Ovale (PFO) Closure in Cryptogenic Stroke: A Case Study.

Patent foramen ovale (PFO) exists in 20-25% of the adult population, and about 40% of adults who present with cryptogenic stroke (CS) have a PFO. The benefit of intervention has been debated with regard to stroke prevention given the high risk of postoperative atrial fibrillation (AF). In light of this, clinical decision-making is guided by PFO-Associated Stroke Causal Likelihood (PASCAL) classification and Risk of Paradoxical Embolism (RoPE) score analysis.