Publications by authors named "Grazielle Ribeiro Goes"

Article Synopsis
  • Cyperus articulatus L. (priprioca) is traditionally used in the Amazon for its aromatic properties and medicinal benefits, particularly for treating inflammatory diseases using its rhizomes.
  • This study explores the phytochemistry and the anti-inflammatory and pain-relieving (antinociceptive) effects of its essential oil (CAEO) through laboratory tests on cells and living mice.
  • Results indicated that CAEO significantly reduced inflammatory markers in cell cultures and lowered leukocyte migration and pain responses in mice, highlighting its potential as a natural remedy for inflammation and pain.
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Chronic ethanol consumption is a leading cause of mortality worldwide, with higher risks to develop pulmonary infections, including infections. Mechanisms underlying increased susceptibility to infections are poorly understood. Chronic ethanol consumption induced increased mortality rates, higher burden and reduced neutrophil recruitment into the airways.

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Trypanosoma cruzi is exposed to oxidative stresses during its life cycle, and amongst the strategies employed by this parasite to deal with these situations sits a peculiar trypanothione-dependent antioxidant system. Remarkably, T. cruzi's antioxidant repertoire does not include catalase.

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Background: Reactive oxygen species (ROS) protect the host against a large number of pathogenic microorganisms. ROS have different effects on parasites of the genus Leishmania: some parasites are susceptible to their action, while others seem to be resistant. The role of ROS in L.

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