Plasma citrate levels as a potential biomarker for glaucoma.

Purpose: To determine the possibility of plasma citrate as a biomarker in patients with glaucoma.

Methods: Twenty-one consecutive Caucasian patients with glaucoma and 21 sex- and age-matched controls were investigated. Plasma citrate, plasma creatinine, urine citrate, and urine creatinine were analyzed by ion chromatography.

Retinal vascular diameter in young subjects with a vasospastic propensity.

Purpose: Retinal vascular diameters have recently been shown not to be related to an increased risk of open-angle glaucoma. Because vasospastic propensity has been suggested to represent a risk factor for various ocular diseases, especially glaucoma, the steady-state retinal vascular diameter in subjects with a propensity for systemic vascular dysregulation was compared with a group of age-matched gender-matched controls.

Methods: Thirty healthy non-smoking individuals [female/male 26/4; mean +/- SD age 22.