Publications by authors named "Graziana Scialpi"
Article Synopsis
- The study focuses on pediatric-onset multiple sclerosis (POMS) patients, who often face cognitive issues, and examines how natalizumab (NTZ) affects their cognitive function compared to adult-onset multiple sclerosis (AOMS) patients.
- Involving 63 patients, researchers monitored cognitive performance using the Symbol Digit Modalities Test (SDMT) over at least 24 months, noting significant cognitive improvement in both POMS and AOMS, with POMS showing greater gains.
- Results suggest that natalizumab not only helps manage disease activity but also enhances cognitive function in POMS, making it a promising treatment option for younger patients.
Background: In multiple sclerosis (MS), imaging biomarkers play a crucial role in characterizing the disease at the time of diagnosis. MRI and optical coherence tomography (OCT) provide readily available biomarkers that may help to define the patient's clinical profile. However, the evaluation of cortical and paramagnetic rim lesions (CL, PRL), as well as retinal atrophy, is not routinely performed in clinic.
View Article and Find Full Text PDFTele-neuropsychology, i.e., the application of remote audio-visual technologies to neuropsychological evaluation or rehabilitation, has become increasingly popular and widespread during and after the COVID-19 pandemic.
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