Comparison between liquid and tablet formulations of levothyroxine in the initial treatment of congenital hypothyroidism.

Objective: To evaluate the effects of liquid (drops) and tablet formulations of levothyroxine in homogeneous groups of infants with congenital hypothyroidism (CH) as diagnosed through neonatal screening.

Study Design: Forty-two consecutive infants with CH were subdivided into 2 groups consisting of infants with the severe or the moderate/mild form. For each form, the infants with CH were randomly assigned to receive liquid (group 1) or tablet (group 2) formulation.

Psychological and behavioural aspects in children and adolescents with congenital hypothyroidism diagnosed by neonatal screening: comparison between parents' and children's perceptions.

Objective: To compare the psychological adjustment and behaviour of congenital hypothyroidism (CH) children and their parents with a control group.

Study Design: A cross-sectional study was carried out with 84 CH subjects diagnosed by neonatal screening (range 2.7-18.