"The Boundless Realm Where All Form Lies". Representing Imagination at the Crossway Between Literary and Neurocognitive Studies.

According to ancient texts on poetics, the concept of representation is deeply bound to that of "mimesis;" this last was intended in two main ways: as "imitation" and as "world construction." In Aristotle's , mimesis is theorized as the main form of "world simulation," giving rise to the complex universe of fiction. The concept of simulation plays a pivotal role in the neurocognitive theories on the embodied mind: within this frame, embodied simulation is intended as a functional prelinguistic activation of the human sensorimotor mechanism.

Burke's "sensitive" sublime rooted in brain and body versus Kant's transcendental concept in the German Romantic discourse.

During the 18th century, debates about what constituted the sublime flourished in Europe, and particularly in Germany. These debates were nourished by two different visions: The Kantian concept supposed that the sublime is supra-sensible and rooted in reason (Logos) rather than in the object, thus provoking a mental state of tension between nature and art; Edmund Burke's concept, on the other hand, conceived of the sublime as a bodily immersive experience, which we here define as "sensitive" sublime. In summary, Burke's view of the sublime is rooted in the senses and not in the power of reason, unlike Kant's.

Activity of budesonide on nasal neutrophilic inflammation and obstruction in children with recurrent upper airway infections. A preliminary investigation.

Objective: While it is widely accepted that inhaled glucocorticosteroids represent an effective treatment for allergic rhinitis, little is known on the specific effects of this therapeutic approach in other upper airway disorders of childhood. The aim of the study was to evaluate the improvement of clinical symptoms and changes in local cellular inflammatory reaction induced by budesonide inhalation suspension in children with recurrent nasal infections using budesonide inhalation suspension delivered by Rinowash, a nebulizer designed to treat upper airway structures.

Methods: In a randomized, controlled-open study, 14 children (5.