Is conventional urinary cytology still reliable for diagnosis of primary bladder carcinoma? Accuracy based on data linkage of a consecutive clinical series and cancer registry.

Objective: Reported urine cytology accuracy, particular sensitivity, is highly variable. We evaluated the accuracy of urinary cytology for primary bladder cancer using population data linkage to provide valid estimates.

Study Design: Consecutive cytology tests processed through a major service between January 2000 and December 2004 were linked to a regional population cancer registry (allowing outcome ascertainment).

Reliability of sparing Papanicolaou test conventional reading in cases reported as No Further Review at AutoPap-assisted cytological screening: survey of 30,658 cases with follow-up cytological screening.

Background: AutoPap-assisted smear reading has been proposed prior to conventional manual reading; the latter may be unnecessary for cases reported as No Further Review (NFR) and would be required for cases reported as Review (REV).

Methods: The authors evaluated comparable concurrent screening cohorts who were undergoing a conventional manual (CONV) or an AutoPap-assisted smear reading within the same screening program. The authors evaluated the prevalence of CIN2+ at repeat screening in subjects 1) with a negative report at conventional Papanicolaou test (CONV- = 9605), 2) with a REV report at AutoPap, followed by a negative conventional reading (REV- = 17,576), and 3) with a NFR report at AutoPap, followed by a negative rapid review (NFR- = 3477) at previous (baseline) screening.

Quality control of the autopap screening system employed as a primary screening device: rapid review of smears coded as no further review.

Aims And Background: Automated reading of smears is increasingly used in cervical screening, and quality control procedures to check its performance are required. The aim of the present study was to evaluate the usefulness of rapid review of all smears coded as "no further review" (NFR) by the AutoPap system as a quality control procedure.

Methods: From 2002-2005, 153,269 smears were processed by AutoPap at the Centro per lo Studio e la Prevenzione Oncologica of Florence, Italy, and 24,503 (15.

A feasibility study of the use of the AutoPap screening system as a primary screening and location-guided rescreening device.

Background: The AutoPap 300 QC system (Tripath Imaging, Inc., Burlington, NC) is an automated device that was designed to screen conventionally prepared cervical smears and, more recently, thin-layer slide preparations. The system has been tested in large clinical trials.

Conventional pap smear and liquid-based cervical cytology smear: comparison from the same patient.

Background: The results of blind reading of smears obtained with liquid-based cytology in patients previously screened by conventional cytology were compared.

Material And Methods: Cases selected for the study were a consecutive series of 99 subjects undergoing colposcopy within the screening program of the Florence District. The Pap test samples were processed utilizing the Thin Prep 2000 (Cytyc Corporation, Boxborough, MA).