C-reactive protein as an early predictor of gestational diabetes mellitus.

Objective: To assess whether C-reactive protein at the beginning of the midtrimester is significantly increased in patients who subsequently develop gestational diabetes mellitus (GDM).

Study Design: A total of 72 subjects who underwent a Down screening program between the 14th and 16th weeks of gestation were studied: 32 developed GDM, and 40 were controls. The C-reactive protein serum levels were evaluated in all patients.