Publications by authors named "Grazia De Ninno"
Article Synopsis
- The study investigates the link between long COVID gastrointestinal symptoms and post-infection gut-brain interaction disorders, aiming to uncover the mechanisms behind these long-term issues.
- Eighty-six individuals who recovered from SARS-CoV-2 infection were evaluated for GI symptoms, inflammation, and permeability, with specific questionnaires used to assess their conditions.
- Results indicated that 43% of participants reported long-term GI symptoms, but those without symptoms had higher intestinal inflammation levels, suggesting local inflammatory mechanisms may not be the primary cause of GI complaints in long COVID.
: Heart failure (HF) represents a major health burden. Although several treatment regimens are available, their effectiveness is often unsatisfactory. Growing evidence suggests a pivotal role of the gut in HF.
View Article and Find Full Text PDFIntroduction: CSF Neurofilament light chain(NfL) is a promising biomarker of neurodegeneration, but its utility in discriminating between Alzheimer's disease(AD) and frontotemporal dementia(FTD) is limited.
Methods: 105 patients with clinical-biological diagnosis of mild cognitive impairment(MCI) due to AD (N = 72) or clinical diagnosis of FTD (N = 33) underwent neuropsychological assessment and CSF Aβ42/40, p-tau181, total-tau and NfL quantification. Group comparisons, correlations between continuous variables and ROC curve analysis were carried out to assess NfL role in discriminating between MCI due to AD and FTD, exploring the associations between NfL, ATN biomarkers and neuropsychological measures.
Introduction: The present cross-sectional study aimed to compare the prevalence, the characteristics of post-dialysis fatigue and the length of recovery time after hemodialysis in prevalent end-stage renal disease patients (ESRD) receiving bicarbonate hemodialysis (HD) or hemodiafiltration (HDF).
Methods: Patients were suffering from post-dialysis fatigue if they spontaneously offered this complaint when asked the open-ended question: "Do you feel fatigued after dialysis?". Moreover, each patient was invited to rate the intensity, duration, and frequency of post-dialysis fatigue from 1 to 5.