Pharmacogenetics in the clinical analysis laboratory: clinical practice, research, and drug development pipeline.

: Over the last decade, the spread of next-generation sequencing technology along with the rising cost in health management in national health systems has led to widespread use/abuse of pharmacogenetic tests (PGx) in the practice of many clinical disciplines. However, given their clinical significance, it is important to standardize these tests for having an interaction with the clinical analysis laboratory (CAL), in which a PGx service can meet these requirements. : A diagnostic test must meet the criteria of reproducibility and validity for its utility in the clinical routine.