In vivo molecular imaging for planning radiation therapy of gliomas: an application of 1H MRSI.

Gliomas are infiltrative lesions that typically have poorly defined margins on conventional magnetic resonance (MR) and computed tomography (CT) images. This presents a considerable challenge for planning radiation and other forms of focal therapy, and introduces the possibility of both under-treating macroscopic tumor, and over-treating regions of normal brain tissue. New therapy systems are able to deliver radiation more precisely and accurately to irregular three-dimensional target volumes, and have placed a premium on definition of the spatial extent of the lesion.

Metabolic imaging of low-grade gliomas with three-dimensional magnetic resonance spectroscopy.

Purpose: The role of radiotherapy (RT) seems established for patients with low-grade gliomas with poor prognostic factors. Three-dimensional (3D) magnetic resonance spectroscopy imaging (MRSI) has been reported to be of value in defining the extent of glioma infiltration. We performed a study examining the impact MRSI would have on the routine addition of 2-3-cm margins around MRI T2-weighted hyperintensity to generate the treatment planning clinical target volume (CTV) for low-grade gliomas.

Registration of magnetic resonance spectroscopic imaging to computed tomography for radiotherapy treatment planning.

The incorporation of multiple imaging modalities into radiotherapy treatment planning offers the potential to improve identification of regions of pathology. This work outlines and evaluates a methodology for registration of magnetic resonance images (MRI) and spectroscopic images (MRSI) to computed tomography (CT) images, and visualization of the multimodality data on the treatment planning workstation. Volumetric magnetic resonance images were acquired during an examination prior to the initiation of radiotherapy.

MR-spectroscopy guided target delineation for high-grade gliomas.

Purpose: Functional/metabolic information provided by MR-spectroscopy (MRSI) suggests MRI may not be a reliable indicator of active and microscopic disease in malignant brain tumors. We assessed the impact MRSI might have on the target volumes used for radiation therapy treatment planning for high-grade gliomas.

Methods And Materials: Thirty-four patients (22 Grade III; 12 Grade IV astrocytomas) were evaluated; each had undergone MRI and MRSI studies before surgery.

Serial proton MR spectroscopic imaging of recurrent malignant gliomas after gamma knife radiosurgery.

Background And Purpose: The diagnosis of brain tumors after high-dose radiation therapy is frequently limited by the lack of metabolic discrimination available with conventional imaging methods. The purpose of this study was to use proton MR spectroscopy to investigate serial changes in recurrent malignant gliomas after gamma knife radiosurgery to characterize tissue response to high-dose radiation.

Methods: Eighteen patients with recurrent gliomas were studied with MR imaging and 3D proton MR spectroscopic imaging at the time of radiosurgery and at regular time points thereafter.

Nuchal-type fibroma in two related patients with Gardner's syndrome.

Nuchal-type fibroma is a distinct subcutaneous and dermal fibrous tissue proliferation that has been previously definitely identified in one patient with Gardner's syndrome and has been possibly present in two others. Gardner's syndrome is an autosomal-dominant condition with variable expressivity that comprises epidermoid cysts, fibrous tumors, osteomas, intestinal polyposis, as well as other findings. We report two cases of nuchal-type fibroma presenting in a 13-year-old boy in the right upper back and in his 60-year-old grandfather in the upper chest at the posterior axillary line.

A preliminary study of the prognostic value of proton magnetic resonance spectroscopic imaging in gamma knife radiosurgery of recurrent malignant gliomas.

Objective: The goal of this study was to investigate the use of proton magnetic resonance spectroscopic imaging as a prognostic indicator in gamma knife radiosurgery of recurrent gliomas.

Methods: Thirty-six patients with recurrent gliomas were studied with proton magnetic resonance spectroscopic imaging at the time of radiosurgery, and with conventional magnetic resonance imaging examinations at regular time intervals until the initiation of a new treatment strategy. Patients were categorized on the basis of their initial spectroscopic results, and their performance was assessed in terms of change in contrast-enhancing volume, time to further treatment, and survival.

1996 summary: National Hospital Discharge Survey.

Objectives: This report presents national estimates of the use of non-Federal short-stay hospitals in the United States during 1996. Numbers and rates of discharges, diagnoses, and procedures are shown by age and sex. Discharges are also shown by geographic region of hospital.

Maintaining a computer-based patient education library.

The demand for patient education, both from patients themselves and from accreditation agencies for health and managed care organizations, is becoming more insistent. This article outlines the components of a system that maintains a library of computer-based patient education handouts that can be quickly integrated into a physician's practice.

Single-layer continuous colon and rectal anastomosis using monofilament absorbable suture (Maxon): study of 500 cases.

Purpose: The study purpose was to evaluate the results of continuous, single-layer colon and rectal anastomoses using a monofilament absorbable suture material (Maxon).

Methods: Four hundred ninety-two consecutive patients undergoing five hundred colon and rectal anastomoses with the above technique were evaluated for outcome, including anastomotic leakage, stricture, and other complications, by means of chart review.

Results: Three patients (0.

National hospital discharge survey: annual summary, 1996.

Objectives: This report presents national estimates of the use of non-Federal short-stay hospitals in the United States during 1996 and selected trend data. Estimates are provided by demographic characteristics of patients discharged, geographic region of hospitals, conditions diagnosed, and surgical and nonsurgical procedures performed. Measurements of hospital use include number and rate of discharges and days of care, and the average length of stay.

Detailed diagnoses and procedures, National Hospital Discharge Survey, 1996.

Objectives: This report presents national estimates of the use of non-Federal short-stay hospitals in the United States during 1996. Estimates of first-listed diagnoses, all-listed diagnoses, days of care for first-listed diagnoses, and all-listed procedures are shown by sex and age of patient and geographic region of hospital.

Methods: The estimates are based on data collected through the National Hospital Discharge Survey for 1996.

National hospital discharge survey.

Objectives: This report presents national estimates of the use of non-Federal short-stay hospitals in the United States during 1995. Estimates are provided by demographic characteristics of patients discharged, geographic region of hospitals, conditions diagnosed, and surgical and nonsurgical procedures performed. Measurements of hospital use include number and rate of discharges and days of care, and the average length of stay.

Detailed diagnoses and procedures, National Hospital Discharge Survey, 1995.

Objectives: This report presents national estimates of the use of non-Federal short-stay hospitals in the United States during 1995. Estimates of first-listed diagnoses, all-listed diagnoses, days of care for first-listed diagnoses, and all-listed procedures are shown by sex and age of patient and geographic region of hospital.

Methods: The estimates are based on data collected through the National Hospital Discharge Survey for 1995.

1995 summary: National Hospital Discharge Survey.

Objectives: This report presents national estimates of the use of non-Federal short-stay hospitals in the United States during 1995. Numbers and rates of discharges, diagnoses, and procedures are shown by age and sex. Discharges are also shown by geographic region of hospital.

National hospital discharge survey: annual summary, 1994.

Objectives: This report presents national estimates of the use of non-Federal short-stay hospitals in the United States during 1994. Estimates are provided by demographic characteristics of patients discharged, geographic region of hospitals, conditions diagnosed, and surgical and nonsurgical procedures performed. Measurements of hospital use include number and rate of discharges and days of care, and the average length of stay.

Detailed diagnoses and procedures, National Hospital Discharge Survey, 1994.

Objectives: This report presents national estimates of the use of non-Federal short-stay hospitals in the United States during 1994. Estimates of first-listed diagnoses, all-listed diagnoses, days of care for first-listed diagnoses, and all-listed procedures are shown by sex and age of patient and geographic region of hospital.

Methods: The estimates are based on data collected through the National Hospital Discharge Survey for 1994.

1994 summary: National Hospital Discharge Survey.

Objectives: This report presents national estimates of the use of non-Federal short-stay hospitals in the United States during 1994. Numbers and rates of discharges, diagnoses, and procedures are shown by age and sex. Discharges are also shown by geographic region of hospital.

Trends in hospital utilization: united states, 1988-92.

This report presents statistics on the utilization of non-Federal short-stay hospitals based on data collected through the National Hospital Discharge Survey for the years 1988 through 1992. The survey is a national sample of hospital records of discharged patients. Estimates are provided by the demographic characteristics of patients discharged, by geographic region of hospitals, and by selected conditions diagnosed and procedures performed.

Detailed diagnoses and procedures, National Hospital Discharge Survey, 1993.

This report presents statistics on conditions diagnosed and surgical and nonsurgical procedures performed in non-Federal short-stay hospitals. The statistics are based on data collected through the National Hospital Discharge Survey from a national sample of the hospital records of discharged inpatients. Estimates of first-listed diagnoses, all-listed diagnoses, days of care for first-listed diagnoses, and all-listed procedures are shown by sex and age of patient and geographic region of hospital.

National Hospital Discharge Survey: annual summary, 1993.

This report presents statistics on the utilization of non-Federal short-stay hospitals based on data collected through the National Hospital Discharge Survey from a national sample of the hospital records of discharged inpatients. Estimates are provided by the demographic characteristics of patients discharged, geographic region of hospitals, conditions diagnosed, and surgical and nonsurgical procedures performed. Measurements of hospital use include frequency, rate and percent of discharges and days of care, and average length of stay.

National Hospital Discharge Survey: annual summary, 1992.

This report presents statistics on the utilization of non-Federal short-stay hospitals based on data collected through the National Hospital Discharge Survey from a national sample of the hospital records of discharged inpatients. Estimates are provided by the demographic characteristics of patients discharged, geographic region of hospitals, conditions diagnosed, and surgical and nonsurgical procedures performed. Measurements of hospital use include frequency, rate and percent of discharges and days of care, and average length of stay.

Detailed diagnoses and procedures, National Hospital Discharge Survey, 1992. Series 13: Data from the National Health Survey.

This report presents statistics on conditions diagnosed and surgical and nonsurgical procedures performed in non-Federal short-stay hospitals. The statistics are based on data collected through the National Hospital Discharge Survey from a national sample of the hospital records of discharged inpatients. Estimates of first-listed diagnoses, all-listed diagnoses, days of care for first-listed diagnoses, and all-listed procedures are shown by sex and age of patient and geographic region of hospital.