Mutations F129L and G143A Confer Resistance to Azoxystrobin in , the Frogeye Leaf Spot Pathogen of Tobacco.

Azoxystrobin is the only synthetic, systemic fungicide labeled in the United States for management of frogeye leaf spot (FLS) of tobacco ( L.), caused by . Though traditionally considered a minor disease in the United States, FLS has recently become yield and quality limiting.