Purpose: To evaluate the utility of Emergency Department (ED) assessment of intraocular pressure (IOP) and visual acuity (VA) measurements as a screening tool for abnormal IOP and VA on ophthalmology exams.
Patients And Methods: This retrospective cross-sectional study reviewed eye-related ED visits between February 1, 2022, and January 31, 2023, at Harborview and University of Washington Medical Centers (Seattle, WA) with same-day ophthalmology consultation. Electronic medical records were reviewed for right eye and left eye IOP and VA obtained by ED and ophthalmology services.
Objective: To compare results of simulator-based vs traditional training of medical students in direct ophthalmoscopy.
Design: Randomized controlled trial.
Methods: First-year medical student volunteers completed 1 hour of didactic instruction regarding direct ophthalmoscopes, fundus anatomy, and signs of disease.
While various tools such as the International Prognostic Index (IPI) and its derivatives exist for risk-stratification of diffuse large B-cell lymphoma (DLBCL) at diagnosis, patient and disease characteristics capable of predicting outcome after high-dose chemotherapy followed by autologous stem cell transplantation (HDC/ASCT) are not clearly defined. We retrospectively analyzed medical records of 111 DLBCL patients (78 relapsed and 33 refractory) who underwent HDC/ASCT at our institution from 2010-2015. After a median follow-up time of 4.
View Article and Find Full Text PDFBackground: Liposomal formulation of anthracyclines provide better systemic and organ-specific tolerance, with potential for less local tissue damage during extravasation. Several small series have reported that most liposomal anthracycline extravasations are consistent with irritant injury without tissue necrosis. There have been no reports published regarding the clinical effects of extravasation of liposomal cytarabine-daunorubicin (CPX-351).
View Article and Find Full Text PDFMultiple novel simian adenoviruses have been isolated over the past years and their potential to cross the species barrier and infect the human population is an ever present threat. Here we describe the isolation and full genome sequencing of a novel simian adenovirus (SAdV) isolated from the urine of two independent, never co-housed, late stage simian immunodeficiency virus (SIV)-infected rhesus macaques. The viral genome sequences revealed a novel type with a unique genome length, GC content, E3 region and DNA polymerase amino acid sequence that is sufficiently distinct from all currently known human- or simian adenovirus species to warrant classifying these isolates as a novel species of simian adenovirus.
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