Derivation of analytical expressions for anomalous reflection in the limit of zero thickness and weakly modulated dielectric grating.

It is known that dielectric gratings exhibit anomalous scattering behavior. At certain incident angles, which are not related to the grating's formula, 100% of the incident beam is reflected and, at other angles, 100% is transmitted. In this paper, analytical expressions are derived, for the first time, to the best of our knowledge, for these angles in the regime of narrow grating and weak modulation depth.

Ultrafast one-minute electronic detection of SARS-CoV-2 infection by 3CL enzymatic activity in untreated saliva samples.

Since its onset in December 2019, severe acute respiratory syndrome coronavirus 2, SARS-CoV-2, has caused over 6.5 million deaths worldwide as of October 2022. Attempts to curb viral transmission rely heavily on reliable testing to detect infections since a large number of transmissions are carried through asymptomatic individuals.

Guidance for the diagnosis and treatment of hypolipidemia disorders.

The Abetalipoproteinemia and Related Disorders Foundation was established in 2019 to provide guidance and support for the life-long management of inherited hypocholesterolemia disorders. Our mission is "to improve the lives of individuals and families affected by abetalipoproteinemia and related disorders". This review explains the molecular mechanisms behind the monogenic hypobetalipoproteinemia disorders and details their specific pathophysiology, clinical presentation and management throughout the lifespan.

Autosomal recessive congenital ichthyosis caused by a pathogenic missense variant in CLDN1.

Autosomal recessive congenital ichthyosis (ARCI) refers to a large and genetically heterogenous group of non-syndromic disorders of cornification featuring diffuse scaling. Ichthyosis, leukocyte vacuoles, alopecia, and sclerosing cholangitis (ILVASC) syndrome is a rare autosomal recessive syndromic form of ichthyosis. The disease usually results from premature termination codon-causing pathogenic variants in CLDN1 encoding CLAUDIN-1 (CLDN1).

Rapid Collection and Aptamer-Based Sensitive Electrochemical Detection of Soybean Rust Fungi Airborne Urediniospores.

Plants are the central source of food for humans around the world. Unfortunately, plants can be negatively affected by diverse kinds of diseases that are responsible for major economic losses worldwide. Thus, monitoring plant health and early detection of pathogens are essential to reduce disease spread and facilitate effective management practices.

Diversely Doped Uniform Silicon Nanotube Axial Heterostructures Enabled by "Dopant Reflection".

Here, we propose a novel method for the synthesis of extremely uniform, diversely doped silicon nanotube heterostructures. The method, comprising a simple two-step synthesis, exploits the use of a Ge nanowire sacrificial core upon which a multidoping axial pattern can be easily obtained, that is enclosed in an intrinsic Si shell. The Ge-Si core-shell structure is then heated to 750 °C, allowing the migration of dopant elements from the Ge core directly into the Si shell.

Mitigating weak dispersion in affordable RF-over-fiber channels.

A dispersion-compensating filter for next-generation low-cost analog and digital optical links is developed. In these high-frequency optical channels, even weak dispersion can be detrimental to data encoding (e.g.

Fundamental limitations of dispersion mitigation filters.

We investigate the fundamental limitations of dispersion mitigation filters. By analyzing the dispersion compensating process from basic principles, we demonstrate how a digital filter can mitigate arbitrarily weak dispersion without oversampling. We calculate the maximum distance the signal can pass with and without dispersion compensation, beyond which no data decoding is possible.

Vapor Trace Collection and Direct Ultrasensitive Detection of Nitro-Explosives by 3D Microstructured Electrodes.

The development of a rapid, sensitive, and selective real-time detection method for explosives traces may have an enormous impact on civilian national security, military applications, and environmental monitoring. However, real-time sensing of explosives still possesses a huge analytical hurdle, rendering explosives detection an issue of burning immediacy and an enormous current challenge in terms of research and development. Even though several explosives detection methods have been established, these approaches are typically time-consuming, need relatively large equipment, demand sample preparation, require a skilled operator, and lack the capability to do high-throughput real-time detection, thus strongly constraining their mass deployment.

Propagation of chirped rectangular pulses in dispersive media: analytical analysis.

Analytical smooth rectangular (ASR) pulses have shown to be useful in optical communications. ASR pulses can be cascaded, and therefore they can be very useful in non-return-to-zero communication protocols. Moreover, unlike super-Gaussian (SG) pulses, the propagation of ASR pulses in dispersive media can be expressed in analytical forms (in both time and frequency domains).

Robust [Formula: see text] symmetry of two-dimensional fundamental and vortex solitons supported by spatially modulated nonlinearity.

The real spectrum of bound states produced by [Formula: see text]-symmetric Hamiltonians usually suffers breakup at a critical value of the strength of gain-loss terms, i.e., imaginary part of the complex potential.

Pillararene-Based Two-Component Thixotropic Supramolecular Organogels: Complementarity and Multivalency as Prominent Motifs.

Rationally designed two-component supramolecular organogels based on multiple chemical interactions between percarboxylato- and peramino-pillararenes are described. Mixing low concentration solutions (<1 % w/v) of decacarboxylato-pillar[5]arene (1) with decaamino-pillar[5]arenes (2 b-d) affords, rapidly and without heating, organogels displaying an exceptional combination of properties. These supramolecular organogels, the characteristics of which are tunable, were found to be thixotropic and thermally stable, with T values in some cases exceeding the boiling point of the embedded solvent.

Multicolor Spectral-Specific Silicon Nanodetectors based on Molecularly Embedded Nanowires.

Silicon-based photodetectors cannot distinguish between different wavelengths. Therefore, these detectors relay on color-specific filters to achieve color separation. Color filters add complexity to color sensitive device fabrication, and hinder miniaturization of such devices.

Controlled Formation of Radial Core-Shell Si/Metal Silicide Crystalline Heterostructures.

The highly controlled formation of "radial" silicon/NiSi  core-shell nanowire heterostructures has been demonstrated for the first time. Here, we investigated the "radial" diffusion of nickel atoms into crystalline nanoscale silicon pillar 11 cores, followed by nickel silicide phase formation and the creation of a well-defined shell structure. The described approach is based on a two-step thermal process, which involves metal diffusion at low temperatures in the range of 200-400 °C, followed by a thermal curing step at a higher temperature of 400 °C.

Affordable dispersion mitigation method for the next generation RF-over-fiber optical channels.

Next-generation analog radio frequency over fiber (RFoF) links will require dispersion compensation. Most dispersion compensation methods are based on additional optical elements. Therefore, these solutions may be inadequate for low-cost channels.

Prenatal diagnosis of biliary atresia: A case series.

Background: Biliary atresia is a progressive disease presenting with jaundice, and is the most common indication for liver transplantation in the pediatric population. Prenatal series have yielded conflicting results concerning a possible association between BA and prenatal nonvisualization of the gallbladder.

Aims: This retrospective case series was performed to assess the association between biliary atresia, prenatal nonvisualization of the gallbladder and other sonographic signs.

Affordable dispersion mitigation with an analog electrical filter.

A new method for dispersion mitigation is presented for low-cost and simple networks. The method does not require dispersion-compensating fibers, special optical filters, coherent detection, or external modulation. It can work in a direct modulation scheme and with a standard optical detector.

Nanodicing Single Crystalline Silicon Nanowire Arrays.

Here, we demonstrate a novel method for the production of single-crystal Si nanowire arrays based on the top-down carving of Si-nanowall structures from a donor substrate, and their subsequent controlled and selective harvesting into a sacrificial solid material block. Nanosectioning of the nanostructures-embedding block by ultramicrotome leads to the formation of size, shape, and orientation-controlled high quality nanowire arrays. Additionally, we introduce a novel approach that enables transferring the nanowire arrays to any acceptor substrate, while preserving their orientation, and placing them on defined locations.

Study of a simple model for the transition between the ballistic and the diffusive regimes in diffusive media.

A Monte Carlo simulation was utilized to investigate a simple model for the transition between the ballistic and the diffusive regimes in diffusive media. The simulation focuses on the propagation of visible and near-infrared light in biological tissues. This research has mainly two findings: (1) the transition can be described, as was found experimentally, with good accuracy by only two terms (ballistic and diffusive).

Hepatitis C Virus in Children: Deferring Treatment in Expectation of Direct-Acting Antiviral Agents.

The major route of hepatitis C virus (HCV) infection in the pediatric age group is vertical, with infection occurring in up to 5% of infants born to mothers positive for HCV-RNA. The natural course of pediatric HCV infection is characterized by a high rate of spontaneous clearance, an asymptomatic clinical course, and normal or mild histologic changes. Cirrhosis is reported in 1-2% of children, and progression to severe chronic liver disease and HCC occurs 20-30 years after infection.

Generic propagation of beams with sharp spatial boundaries.

The propagation of spatial beams with initially sharp transverse boundaries is investigated theoretically and experimentally with the paraxial wave equation (PWE). The sharp boundaries generate a universal pattern, which is a consequence of the Schrödinger-like nature of the paraxial dynamics. As a consequence, an approximate analytical expression can be derived for the longitudinal propagation dynamics of the beam.

Homozygous deletion of TRMT10A as part of a contiguous gene deletion in a syndrome of failure to thrive, delayed puberty, intellectual disability and diabetes mellitus.

Two recent reports describe a new syndrome of intellectual disability, short stature, microcephaly, and young onset diabetes or disturbed glucose metabolism in association with inactivating mutations in the TRMT10A gene. We investigated the clinical spectrum presented by a 17-year-old female with a homozygous contiguous gene deletion involving the TRMT10A gene. From infancy, she presented with failure to thrive and microcephaly.

Cytokine profile of food-allergic post-liver transplant children is identified by high levels of IL-5 and low IL-10 secretion from patients' peripheral blood mononuclear cells.

Severe allergic reaction to food following liver transplantation is a well-known phenomenon. However, the mechanisms underlying this phenomenon are not yet elucidated. This study aimed to reveal the nature of the immune response in post-transplanted allergic patients and compare them to non-allergic transplanted as well as allergic and non-allergic control subjects, with focus on cytokine milieu.

Ballistic imaging of biological media with collimated illumination and focal plane detection.

A simple, affordable method for imaging through biological tissue is investigated. The method consists of (1) imaging with a wavelength that has a relatively small scattering coefficient (1310 nm in this case) and (2) collimated illumination together with (3) focal plane detection to enhance the detection of the ballistic photons relative to the diffusive light. We demonstrate ballistic detection of an object immersed in a 1-cm-thick cuvette filled with 4% Intralipid, which is equivalent to ∼1 to 2 cm of skin tissue.

Improvement in allergic and nonallergic rhinitis: A secondary benefit of adenoidectomy in children.

Chronic rhinitis (CR) is a common disorder in children. Allergic rhinitis (AR) is a risk factor for CR, and children with AR tend to suffer more from hypertrophic adenoids than do patients with nonallergic rhinitis (NAR). Few studies have addressed the issue of alleviating symptoms of pediatric CR or AR following adenoidectomy alone.