Publications by authors named "Grandner M"

Rationale: Obstructive sleep apnea (OSA) is a common condition that is usually treated by continuous positive airway pressure (CPAP) therapy, but poor adherence is common and is associated with worse patient outcomes and experiences. Patient satisfaction is increasingly adopted as a quality indicator by healthcare systems.

Objective: We tested the hypothesis that peer-driven intervention effected through interactive voice-response(PDI-IVR) system leads to better patient satisfaction (primary outcome), care-coordination, and CPAP adherence when compared to active-control.

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Article Synopsis
  • The National Heart, Lung, and Blood Institute held a virtual workshop in September 2022 to explore effective methods for measuring diet, physical activity, and sleep, identifying research gaps and future directions.
  • Key discussions highlighted the integration of self-reported data from questionnaires with device-based assessments like wearables and biomarkers to improve chronic disease understanding.
  • The workshop emphasized the need for data harmonization and standardization to enhance analysis through AI and machine learning, ultimately aiming to improve accuracy and comparability of lifestyle behavior studies.
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Fruit and vegetable intake (FVI), moderate-to-vigorous physical activity (MVPA), and sleep duration are each independently associated with cancer-related and general health outcomes among cancer survivors. Past research suggests that health behaviors cluster among cancer survivors, with caregivers demonstrating similar patterns. This analysis examined co-occurrence of FVI, MVPA, and sleep duration among cancer survivors and informal cancer caregivers and identified sociodemographic and clinical correlates of health behavior engagement.

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Study Objectives: Immunity is influenced by sleep and the circadian rhythm. Healthcare workers are predisposed to both insufficient sleep and circadian disruption. This study aimed to evaluate the relationship between sleep and work characteristics and the antibody response to the mRNA SARS-CoV-2 vaccine BNT162b2.

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Objectives: Regional sleep differences may reflect other important indicators of health and well-being. Examining sleep health at the regional level can help inform policies to improve population health. We examined the relationship between neighborhood-level adult sleep health (modeled in this study via adult sleep duration) and other health metrics and multiple indicators of child-relevant opportunity.

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Study Objectives: The 3P and 4P models represent illness severity over the course of insomnia disorder. The 3P model suggests that illness severity is worst during acute onset. The 4P model suggests that illness severity crescendos with chronicity.

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Article Synopsis
  • - Collegiate athletes face unique challenges that affect their academic performance and health due to extensive travel, competition schedules, and practice commitments, especially with changes in athletic conferences leading to longer travel times.
  • - Increased east-west travel can disrupt sleep patterns, causing jet lag and negatively impacting both the physical and mental health of student-athletes.
  • - Experts propose practical solutions, like bedtime protocols and scheduled naps, urging athletic departments to collaborate with sleep specialists to enhance the wellbeing of athletes and support staff.
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Background: Sleep problems are common and costly in the US military. Yet, within the military health system, there is a gross shortage of trained specialist providers to address sleep problems. As a result, demand for sleep medicine care far exceeds the available supply.

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Objectives: The present study investigated the roles birthplace and acculturation play in sleep estimates among Hispanic/Latino population at the US-Mexico border.

Measures: Data were collected in 2016, from  = 100 adults of Mexican descent from the city of Nogales, AZ, at the US-Mexico border. Sleep was assessed with the Pittsburgh Sleep Quality Index (PSQI), Insomnia Severity Index categorized as none, mild, moderate, and severe, and Multivariable Apnea Prediction Index (MAP) categorized as never, infrequently, and frequently.

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Objectives: The present study evaluated whether completers of a 12-week app-based, personalized text supported sleep coaching program demonstrated improvements in sleep continuity, sleep duration, and reduced use of sleep aids.

Methods: Data were obtained from Sleep Reset, a 12-week consumer product that offers app-based sleep education and monitoring, along with personalized text-based sleep coaching provided by live coaches. 564 completers were included in the study.

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Background: The relationship between adverse childhood experiences and sleep disturbances in collegiate athletes was examined.

Methods: A questionnaire was completed by 189 National Collegiate Athletic Association (NCAA) Division-I male (n = 102) and female (n = 87) student-athletes recruited by flyers on one campus. Variables included adverse childhood experiences (self-reported), insomnia (Insomnia Severity Index), sleep quality (Pittsburgh Sleep Quality Index), fatigue (Fatigue Severity Scale), and sleep duration (self-reported).

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Study Objectives: Obstructive sleep apnea (OSA) and poor quality of sleep negatively impacts health-related quality of life in adults, but few studies have evaluated the association between sleep disturbance (eg, OSA, inadequate sleep) and health-related quality of life domains (eg, family relations, life satisfaction) in children.

Methods: Children ages 8-17 years referred to a sleep center for routine polysomnography from April 2022 to August 2022 were approached to participate in the study, and children visiting the department of pediatrics for their wellness visit were recruited for comparisons. Statistical analysis was conducted using R 3.

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Background: Insomnia disorder is a highly prevalent, significant public health concern associated with substantial and growing health burden. There are limited real-world data assessing the burden of insomnia disorder on daytime functioning and its association with comorbidities. The objective of this study was to leverage large-scale, real-world data to assess the burden of untreated insomnia disorder in terms of daytime impairment and clinical outcomes.

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Study Objectives: Near-infrared light exhibits several therapeutic properties, but little is known about the benefits to sleep and daytime function. The purpose of this study was to investigate the effects of red and near-infrared exposure before bed on sleep and next-day function.

Methods: Thirty adults (30-60 y) with a self-reported sleep complaint but without a sleep disorder participated in a randomized, sham-controlled study for a duration of 5 weeks.

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Objectives: This real-world study aimed to characterize the impact of illness of excessive daytime sleepiness (EDS) in patients with obstructive sleep apnea (OSA) who are adherent to continuous positive airway pressure (CPAP).

Methods: This cross-sectional study surveyed participants in Evidation Health's Achievement app (November 2020-January 2021), a mobile consumer platform that encourages users to develop healthy habits and provides incentives to participate in research. Participants were US-resident adults who self-reported a physician diagnosis of OSA and adherence to CPAP (≥4 hours/night, ≥5 nights/week) for≥6 months.

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Study Objectives: This study assessed perceptions and attitudes of sleep medicine providers regarding consumer sleep technology (CST).

Methods: A convenience sample of n = 176 practicing sleep medicine and behavioral sleep medicine experts was obtained using social media and the American Academy of Sleep Medicine directory. Providers completed a questionnaire that assessed perceptions and attitudes about patient use of CST in the clinical setting.

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Objective: Insufficient and disturbed sleep are associated with significant morbidity among working-age adults. Poor sleep results in negative health outcomes and increases economic costs to employers. The current systematic review surveyed the peer-reviewed scientific literature and aggregated scientific evidence of sleep-related economic burdens borne by employers.

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Article Synopsis
  • Cancer survivors often struggle with insomnia and depression, which are linked according to the Integrated Sleep and Reward (ISR) Model, highlighting the importance of reward processing in these conditions.
  • A pilot randomized controlled trial tested the effects of a 4-session virtual cognitive behavioral therapy for insomnia (CBT-I) on cancer survivors, focusing on changes in anticipatory and consummatory pleasure alongside depression symptoms.
  • Results indicated that CBT-I helped maintain anticipatory pleasure levels, which were positively associated with reductions in insomnia severity, supporting the ISR Model and suggesting that enhancing pleasure could be a key strategy in treating insomnia and depression in cancer survivors.*
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Objective/background: Cognitive behavioural therapy for insomnia (CBT-I) substantially reduces total wake time (TWT) by the end of treatment. In contrast, total sleep time (TST) does not increase above baseline levels for most patients following 4-8 sessions of treatment. In the 6-12 months following CBT-I, without any further intervention, up to 64% of participants substantially increase their TST (by ≥ 30 min).

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