Publications by authors named "Grandi S"

The photoelectrochemical oxidation of 5-hydroxymethylfurfural (HMF), a biomass-derived intermediate, to 2,5-furandicarboxylic acid (FDCA), a key building block for industrial applications, is a well-studied anodic reaction. This photoelectrochemical (PEC) conversion typically requires an electron mediator, such as TEMPO, regardless of the semiconductor used. Various electrocatalysts can also perform this reaction electrochemically, without additional organic species in the electrolyte.

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Background: In the context of post-traumatic hand rehabilitation, stiffness of the hand joints limits the range of motion (ROM), grip strength, and the possibility of performing simple grasps. Robotic rehabilitation has been widely adopted for hand treatment with neurological patients, but its application in the orthopaedic scenario remains limited. In this paper, a pilot study targeting this population is presented, where the rehabilitation is performed using a powered finger exoskeleton, namely I-Phlex.

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  • Around 5-10% of pancreatic cancer patients don't express CA 19-9, and it's unclear how this affects their cancer severity and prognosis.
  • A study analyzed data from 88,749 pancreatic cancer patients, finding that non-expressors had a higher chance of distant metastasis and a shorter median overall survival compared to those with normal CA 19-9 levels.
  • The findings suggest that patients who are non-expressors of CA 19-9 might need different diagnostic approaches and more aggressive treatment strategies.
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  • Preterm birth (PTB) is a significant cause of neonatal mortality and is associated with higher risks of death later in life, but research on long-term outcomes in North America is limited.
  • This study analyzed data from nearly 5 million births in Canada between 1983 and 1996 to investigate the link between PTB and mortality from birth to age 36.
  • Findings revealed that individuals born preterm had a significantly increased risk of death across all age groups, especially in infancy, highlighting the long-term implications of PTB on health.
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  • The study looked at how certain pregnancy-related health issues, called hypertensive disorders of pregnancy (HDP), relate to serious problems mothers can face after delivery, especially heart issues (cvSMM).
  • It used data from a big hospital study in the U.S. covering deliveries from 2015 to 2019 to figure out these connections.
  • The results showed that mothers with HDP had a higher chance of heart problems compared to those without HDP, and those with a specific condition called HELLP syndrome were at the highest risk.
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  • The study investigates the relationship between labor duration, mode of delivery (cesarean vs. vaginal), and long-term maternal mortality among mothers from the Collaborative Perinatal Project cohort.
  • Findings indicate that 5.9% of the participants underwent a cesarean delivery, and those who had cesarean births were generally older, had higher BMI, and more pre-existing health conditions compared to those with vaginal deliveries.
  • The results show that having a cesarean delivery is significantly associated with an increased risk of all-cause mortality, particularly among first-time mothers (nulliparas).
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Background And Objectives: The widespread adoption of virtual care during the pandemic may not have been uniform across populations, including among paediatric immigrants and refugees. We sought to examine the association between virtual mental healthcare utilisation and immigration factors.

Methods: This population-based cohort study of immigrants and refugees (3-17 years) used linked health administrative databases in Ontario, Canada (March 2020 to December 2021).

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Background: Autoimmune diseases disproportionately impact women and female-specific aspects of reproduction are thought to play a role. We investigated the time-varying association between pregnancy complications and new-onset autoimmune disease in females during the reproductive and midlife years.

Methods: We conducted a population-based cohort study of 1 704 553 singleton births to 1 072 445 females in Ontario, Canada (2002-17) with no pre-existing autoimmune disease.

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  • Maternal hypothyroidism during pregnancy is crucial for fetal development, but its link to metabolic diseases in children is not clear.
  • The objective of the study was to investigate the impact of maternal hypothyroidism on various metabolic conditions (like obesity and diabetes) in children under 18 years old.
  • After reviewing 3221 articles, the study concluded that while there may be a connection between maternal hypothyroidism and increased risks of hypertension and glucose issues in offspring, its effect on obesity remains unclear.
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Individuals with disabilities may require specific medications in pregnancy. The prevalence and patterns of medication use, overall and for medications with known teratogenic risks, are largely unknown. This population-based cohort study in Ontario, Canada, 2004-2021, comprised all recognized pregnancies among individuals eligible for public drug plan coverage.

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Study Question: What is the association between reproductive health history (e.g. age at menarche, menopause, reproductive lifespan) with abdominal adiposity in postmenopausal women?

Summary Answer: Higher visceral adipose tissue (VAT) and subcutaneous adipose tissue (SAT) tissue levels were observed among women with earlier menarche, earlier menopause, and greater parity.

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Introduction: 24 % of abortion in Italy are repeated procedure. The cause of repeated abortion can be traced back to the inadequacy of the contraceptive counseling during the previous admission or to the adoption of an ineffective contraception method. This study aims to evaluate the Italian situation on the perceived quality of contraceptive counselling by patients undergoing abortion.

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Objective: To define major congenital anomaly (CA) subgroups and assess outcome variability based on defined subgroups.

Study Design: This population-based cohort study used registries in Denmark for children born with a major CA between January 1997 and December 2016, with follow-up until December 2018. We performed a latent class analysis (LCA) using child and family clinical and sociodemographic characteristics present at birth, incorporating additional variables occurring until age of 24 months.

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Background: During pregnancy, various maternal IgG antibodies are transferred to the developing fetus, some of which may protect the newborn against infection. If a mother and her fetus have different A, B or O (ABO) blood groups, then transferred maternal antibodies may plausibly protect the infant against infection.

Aim: To determine if maternal-newborn ABO blood group incongruence vs.

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Objective: To describe the mental health trajectories of caregivers of children with medical complexity (CMC) and explore child characteristics associated with below-average caregiver mental health.

Design: A secondary analysis of prospectively collected data from 123 caregivers of children aged <16 years with medical complexity from a multicentre randomised trial conducted from December 2016 to June 2021.

Main Outcome Measure: The Patient-Reported Outcomes Measurement Information System Global Mental Health Scale was used to measure caregivers' self-reported mental health well-being.

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In this issue of , Sheehy et al. report the results of a prospective cohort study that examined the association between hypertensive disorders of pregnancy (HDOP) and the risk of stroke among Black women in the United States. Using data from 42,924 participants in the Black Women's Health Study (BWHS) who were free of cardiovascular disease at baseline, they compared the rates of stroke between women with HDOP and those who did not have HDOP over a median follow-up of 22 years.

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Objective: The underpinning biologics of migraine chronification are not well understood. We aim to investigate the role of the cumulative burden of stress, namely the allostatic load, in migraine chronification.

Methods: This was a cross-sectional study.

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Objective: Mothers whose newborn experiences adversity may neglect their own health to care for their affected infant or following a perinatal death. Weight gain after pregnancy is one measure of maternal self-care. We measured interpregnancy weight gain among women whose child had an adverse perinatal event.

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Virtual reality (VR) is a valuable tool for the treatment and prevention of psychiatric disorders and dysfunctional behaviors. Although VR software is mainly developed following a disorder-specific approach, this randomized controlled trial (RCT) will test the efficacy of a new transdiagnostic VR application (H.O.

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Background: Multifetal gestation could be associated with higher long-term maternal mortality because it increases the risk of pregnancy complications such as preeclampsia and preterm birth, which are in turn linked to postpartum cardiovascular risk.

Objectives: We examined whether spontaneously conceived multifetal versus singleton gestation was associated with long-term maternal mortality in a racially diverse U.S.

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Background: Persons with non-O and Rh-positive blood types are purported to be more susceptible to infection, including SARS-CoV-2, but there remains uncertainty about the degree to which this is so for both non-viral and viral infections.

Methods: We systematically reviewed Embase and PubMed from January 1 1960 to May 31 2022. English-language publications were selected that separately investigated the relation between ABO and/or Rh blood group and risk of SARS-CoV-2 and non-SARS-CoV-2 infection.

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