Publications by authors named "Graham Sutherland"
Leptospirosis is one of the most common zoonotic diseases in the world and endemic in the Caribbean Islands. Bovine leptospirosis is an important reproductive disease. Globally, cattle are recognized as a reservoir host for serovar Hardjo, which is transmitted urine, semen, and uterine discharges, and can result in abortion and poor reproductive performance.
View Article and Find Full Text PDFBackground: The first documented human leptospirosis cases in the U.S. Virgin Islands (USVI) occurred following 2017 Hurricanes Irma and Maria.
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- Taenia solium causes neurocysticercosis (NCC), leading to complications like hippocampal atrophy and adult-onset epilepsy, particularly in developing regions.* -
- Researchers examined brain tissue from rats infected with T. solium, analyzing gene expression related to inflammation and healing after 4 months.* -
- Findings showed overexpression of inflammatory cytokines near the parasite and in distant areas, suggesting that these molecular pathways could link NCC to hippocampal atrophy.*
Neurocysticercosis (NCC) is a helminth infection affecting the central nervous system caused by the larval stage (cysticercus) of Taenia solium. Since vascular alteration and blood-brain barrier (BBB) disruption contribute to NCC pathology, it is postulated that angiogenesis could contribute to the pathology of this disease. This study used a rat model for NCC and evaluated the expression of two angiogenic factors called vascular endothelial growth factor (VEGF-A) and fibroblast growth factor (FGF2).
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