Publications by authors named "Graham R Barr"
Article Synopsis
- - The study explores the link between urinary metal levels and cardiovascular disease (CVD) by analyzing data from 6,418 participants over a ten-year period, focusing on non-essential metals like cadmium and essential metals such as cobalt and zinc.
- - Results showed that higher urinary levels of cadmium, tungsten, uranium, and cobalt were significantly associated with increased coronary artery calcium (CAC) progression, indicating a higher risk of atherosclerotic CVD over time.
- - While cadmium had a strong association with both baseline and ten-year follow-up measures of CAC, the effect of copper and zinc diminished after adjusting for clinical risk factors, suggesting varying impacts of different metals on cardiovascular health.
Aims: Anecdotal reports have suggested increased soft tissue calcification in individuals with long-term exposures to high blood glucose. The association of costal cartilage calcification (CCC), a reliably quantifiable marker obtainable from non-contrast cardiac computed tomography (CT) with cumulative fasting blood glucose (FBG) exposure, is unknown. In this study, we aimed to determine the association between quantified CCC and cumulative glucose exposure using non-contrast coronary artery calcium (CAC) scoring computed tomography (CT) images in the Multi-Ethnic Study of Atherosclerosis (MESA).
View Article and Find Full Text PDFBackground And Aims: Modern tobacco regulatory science requires an understanding of which biomarkers of cardiovascular injury are most sensitive to cigarette smoking exposure.
Methods: We studied self-reported current smokers from the Multi-Ethnic Study of Atherosclerosis. Smoking intensity was defined by number of cigarettes/day and urinary cotinine levels.