Driving on ice: impaired driving skills in current methamphetamine users.

Rationale: Previous research indicates a complex link between methamphetamine (METH) and driving performance. Acute dosing with amphetamines has improved driving-related performance in some laboratory studies, while epidemiological studies suggest an association between METH use, impaired driving, and accident culpability.

Methods: Current METH users were compared to a control group of nonusers on driving simulator performance.

The effect of modafinil following acute CPAP withdrawal: a preliminary study.

Daytime symptoms resulting from obstructive sleep apnea (OSA) include impaired neurobehavioural performance and increased sleepiness. Continuous positive airway pressure (CPAP) reduces these symptoms. However, even compliant users may temporarily withdraw from CPAP treatment resulting in an immediate return of OSA.