Publications by authors named "Graeme Pettifor"
Eur J Pharmacol
December 2011
Article Synopsis
- The study investigates the effects of methylarginines (L-NMMA and ADMA) on nitric oxide (NO) activity in female rat aorta, focusing on differences in basal versus agonist-stimulated NO functions.
- Both L-NMMA and ADMA increased submaximal vasoconstriction caused by phenylephrine, indicating they block basal NO activity, while having minimal impact on relaxation induced by acetylcholine.
- The findings suggest that L-NMMA and ADMA selectively inhibit basal NO activity without significantly affecting agonist-stimulated relaxation responses.
