Coagulation after cytoreductive surgery and hyperthermic intraperitoneal chemotherapy: a retrospective cohort analysis.

Purpose: Cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) benefit patients with peritoneal carcinomatosis. Nevertheless, this therapy is associated with considerable postoperative pain due to the extensive abdominal incision. While epidural analgesia offers efficacious pain control, CRS and HIPEC therapy is associated with perioperative coagulopathy that may impact its use.

Changes in erythropoiesis assessed by reticulocyte parameters during ultralong distance running.

Objective: To investigate the possibility of early changes in erythropoiesis during prolonged exercise being reflected in reticulocyte parameters.

Design: This was a case-control field study of hematological variables in a group of ultramarathon runners competing in a 6-day track race.

Setting: A 6-day ultramarathon in Colac, Australia.