Publications by authors named "Grada A Versteeg"

Article Synopsis
  • The study compares the effectiveness of baricitinib and TNF-inhibitors (TNFi) in treating rheumatoid arthritis (RA) patients who did not respond to conventional treatments.
  • A total of 199 patients were randomized, showing baricitinib to be both non-inferior and superior in achieving meaningful clinical responses at 12 weeks, with a higher percentage of patients reaching specified disease activity targets compared to TNFi.
  • The results suggest that baricitinib may be a more effective initial treatment option than TNFi for RA patients who have failed previous therapies, based on the outcomes measured over 48 weeks.
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Background: Previous research has shown an unclear and inconsistent association between fatigue and disease activity in patients with rheumatoid arthritis (RA). The aim of this study was to explore differences in "between-person" and "within-person" associations between disease activity parameters and fatigue severity in patients with established RA.

Methods: Baseline and 3-monthly follow-up data up to one-year were used from 531 patients with established RA randomized to stopping (versus continuing) tumor necrosis factor inhibitor treatment enrolled in a large pragmatic trial.

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