(Roscoe) mitigates CCl-induced liver histopathology and biochemical derangements through antioxidant, membrane-stabilizing and tissue-regenerating potentials.

The world-wide increasing incidence of liver injury has attracted scientific interest in the exploration of better treatment or adjuvant treatment therapies. This study investigated the effects of methanol extract of (Roscoe) rhizome (MEZOR) in a Wistar rat model of carbon tetrachloride (CCl)-induced liver injury. The study recruited thirty female Wistar rats that received graded doses of MEZOR (determined by its LD) by oral gavage through an oral canula, for 4 consecutive weeks following 1 week oral administration of CCl (0.

Acetonic extract of (Del.) attenuates Cd-induced liver injury: Potential application in adjuvant heavy metal therapy.

Exposure to cadmium (Cd), even at low doses, is of serious health concern because it does not undergo metabolic degradation to less toxic metabolite. Liver injury/disease, with a world-wide increasing incidence, is one of the consequences of exposure to Cd toxicity. This study aimed at determining the effects of acetonic extract of Vernonia amygdalina leaf (AEVAL) in a Wistar rat model of Cd-induced liver injury.