Diacetylcurcumin: a novel strategy against biofilm in root canal disinfection.

We evaluated Diacetylcurcumin (DAC), a derivative of curcumin, for its antibacterial and antibiofilm properties against . Minimum inhibitory concentration (MIC) and minimum bactericidal concentration were determined, along with antibiofilm potential and toxicity in . Additionally, computational analysis was performed to understand its mechanisms of action.