Predictive factors of sleep quality in patients with chronic migraine.

Introduction: One of the factors contributing to transformation of migraine are sleep disorders, which can act as a trigger and/or perpetuating factor in these patients. This study's primary objective was to identify predictive factors related to sleep quality in patients with chronic migraine (CM); the secondary objective was to identify any differences in psychological variables and disability between patients with CM with better or poorer sleep quality.

Methods: A total of 50 patients with CM were included in an observational, cross-sectional study.

Predictive factors of sleep quality in patients with chronic migraine.

Introduction: One of the factors contributing to transformation of migraine are sleep disorders, which can act as a trigger and/or perpetuating factor in these patients. This study's primary objective was to identify predictive factors related to sleep quality in patients with chronic migraine (CM); the secondary objective was to identify any differences in psychological variables and disability between patients with CM with better or poorer sleep quality.

Methods: A total of 50 patients with CM were included in an observational, cross-sectional study.

Widespread mechanical pain hypersensitivity in patients with chronic migraine and temporomandibular disorders: relationship and correlation between psychological and sensorimotor variables.

Objective: This study aimed to assess mechanical hyperalgesia in the trigeminal and extra-trigeminal regions in patients with chronic migraine (CM) and temporomandibular disorders (TMD) in comparison to asymptomatic subjects and to determine the association between sensorimotor variables and psychological and disability variables and evaluate the prediction of a sensorimotor variables though psychological and disability variables in patients with CM and TMD.

Material And Methods: A total of 52 subjects with concomitant CM and TMD and 30 asymptomatic subjects were included in the study. The pressure pain threshold (PPT), maximal mouth opening (MMO) and a series of self-reported factors were compared.

Effects of a Physical Therapy Protocol in Patients with Chronic Migraine and Temporomandibular Disorders: A Randomized, Single-Blinded, Clinical Trial.

Aims: To investigate the effects of adding orofacial treatment to cervical physical therapy in patients with chronic migraine and temporomandibular disorders (TMD).

Methods: A total of 45 participants with chronic migraine and TMD aged 18 to 65 years were randomized into two groups: a cervical group (CG) and a cervical and orofacial group (COG). Both groups continued their medication regimens for migraine treatment and received physical therapy.

[Does medication abuse in patients with chronic migraine influence the effectiveness of preventive treatment with topiramate?].

Introduction: Patients with chronic migraine (CM) and medication abuse are difficult to treat, and have a greater tendency towards chronification and a poorer quality of life than those with other types of headache.

Aim: To evaluate whether the presence of medication abuse lowers the effectiveness of topiramate.

Patients And Methods: A series of patients with CM were grouped according to whether they met abuse criteria or not.

[A comparative study of the effectiveness of topiramate and flunarizine in independent series of chronic migraine patients without medication abuse].

Introduction: Topiramate and onabotulinumtoxin A have proven to be effective in chronic migraine with or without medication abuse according to recent criteria of the International Headache Society's Headache Classification.

Aims: To show that flunarizine is as effective as topiramate in cases of chronic migraine without medication abuse.

Patients And Methods: We conducted a prospective, non-randomised, comparative study of two groups of patients paired by age and sex, with chronic migraine without abuse, who had been treated preventively for the first time with topiramate or flunarizine.

[Triptans in clinical practice: effectiveness, tolerance and patient's satisfaction with medication (TRIPRACLI study)].

Introduction And Aims: This study was aimed determining the effectiveness, tolerance and satisfaction of patients with migraine as regards different triptans, according to the characteristics of their attacks. At the same time it sought to establish a predictive model that can be used to recommend one or another, depending on those characteristics.

Patients And Methods: Retrospective observation-based study conducted in headache units in a number of different centres.

[A study to compare independent groups of patients with episodic migraine who were treated preventively with flunarizine or nadolol].

INTRODUCTION. Flunarizine, with level of evidence A, and nadolol, with evidence level C, would be indicated as preventive treatment of migraine. Yet, no previous studies have been conducted to compare the effectiveness of the two drugs.

[Predisposing factors affecting drop-out rates in preventive treatment in a series of patients with migraine].

Introduction: The drop-out rate among patients receiving preventive treatment for migraine is higher than 30%. This situation is not very widely known and the risk factors that lead patients to drop out from treatment have yet to be identified.

Aim: To evaluate some of the factors that can predispose patients to drop out of preventive treatment.

[Comparative study of the effectiveness of topiramate and nadolol in the preventive treatment of episodic migraine in independent series of patients].

Introduction: Topiramate and nadolol with levels A and C of scientific evidence, respectively, would be indicated as preventive treatments of migraine. To date only one study of satisfaction has been carried out to compare the two pharmaceuticals.

Aim: To compare the effectiveness parameters in independent groups of patients treated preventively with one of the pharmaceuticals from the study.

[Zonisamide in the preventive treatment of refractory migraine].

Introduction: Chronic migraine refractory to preventive treatment is a common clinical situation in general neurology clinics. The aim is to analyse our experience with zonisamide in the preventive treatment of patients with frequent refractory migraine.

Patients And Methods: Those patients with no response or intolerance to topiramate and at least one more preventative received zonisamide.

[Patients with headache and medication abuse. Indicators of response to ambulatory treatment].

Introduction: Patients with headache and medication abuse (HMA) are difficult to treat, have a greater tendency towards chronification and a poorer quality of life than those with other types of headache. AIM. To evaluate the indicators showing that these patients are responding to ambulatory treatment.

[The importance of chronic migraine in a general neurology service].

Introduction: Chronic migraine is a primary headache that is difficult to treat and has an important impact on the patient's quality of life. The international headache classification recently modified the criteria for chronic migraine and therefore few studies have been conducted that analyse groups according to these new criteria. AIM.

[Topiramate in chronic daily headache due to migraine].

Introduction: Chronic daily headache (CDH) includes primary headaches that last more than four hours with a frequency equal or superior to 15 days a month over the last three months. It has a prevalence of 4-5% in the general population and is a frequent reason for visiting the physician in headache units.

Aim: To evaluate the effectiveness of topiramate, as the primary drug, in CDH due to probable chronic migraine with or without medication abuse.

[Topiramate or flunarizine in the preventive treatment of migraine. A comparative study of two series of cases].

Introduction: Both flunarizine and, more recently, topiramate have proved to be effective in the prophylaxis of migraine.

Aim: To compare two independent groups of patients with similar clinical and demographic characteristics who were treated with flunarizine or topiramate as the preferred drug in the prevention of their migraines and to evaluate effectiveness and safety according to the medication they received.

Patients And Methods: All the patients reported more than four episodes a month and/or transformed migraine according to Silberstein's criteria, and had never received prophylactic treatment.

[Effectiveness of topiramate in migraine prophylaxis, an observational study in a consecutive case-serie].

Introduction: Open-label studies and three large and controlled trials had demostrated the efficacy of topiramate in migraine prophylaxis.

Objectives: The objective of this study was to assess the effectiveness and tolerability of topiramate in patients not previously treated with any prophylactic drug.

Patients And Methods: Patients selection was made on sequential patients attending our outpatient clinic.

[Economic evaluation of acute migraine attack treatment with triptans in Spain].

Objective: To perform an economic evaluation of migraine attack treatment comparing standard doses of existing triptans in 2003, and using different outcome measurements of anti-migraine effectiveness.

Methods: A cost-effectiveness analysis was performed from the National Health System perspective, using 2003 prices, comparing almotriptan 12.5 mg, eletriptan 40 mg, naratriptan 2.

[Differences between migraine patients referred to a headache unit or a general neurology service].

Introduction: Migraine accounts for 10% of patients first visits due to neurological reasons in Spain and over half the new visits in headache units (HU) and hence the importance of this pathology.

Aims: The aim of this study is to determine whether there are any differences between migraine patients referred to a general neurology service (GNS) or to a HU.

Patients And Methods: Two groups of patients with migraine were compared: those sent for the first time to a GNS and the others, who were sent directly to a HU.

[Cost effectiveness of treatment with triptanes in Spain].

Introduction: Migraine is a very common disorder and frequent cause of consultation of the neurologist. The triptanes have been a great advance in the treatment of migraine attacks. At present it is the treatment of choice in severe attacks of migraine, but it is more expensive than the other drugs used for this.

[Reasons for requesting neuroimaging studies in the evaluation of primary headache].

Introduction: There is some controversy concerning the need to perform neuroimaging studies in patient complaining of headache. 90% of the people had a complaint of headache during their life, and it is impossible to perform neuroimaging studies in all of them.

Objective: The aim of this study is knowing the reasons for indications neuroimaging studies in the evaluation of primary headaches and the effectiveness at the diagnosis.

[Chronic tension headache in the neurological outpatient clinics].

Introduction: Headache is the commonest cause of neurological consultation in Spain. Chronic tension headache is a common reason for consultation, although diagnosis is difficult.

Objectives: To emphasize the profile of a patient with chronic tension headache and analyze the differences from other groups of neurology patients.

[Burden and management differences between migraine with and without aura in neurology clinics].

Background: Migraine is one of the most important reason of neurological consultation in Spain.

Objective: The aim of the present study was to analyse the profile of the patient with migraine and investigate epidemiological, clinical and therapeutical differences between migraine with aura o without aura.

Patients And Method: For three consecutive months all patients attending for the first time the Neurology clinics of the Health Service of Aragón, were given a specially designed questionnaire.