Safety of immunotherapy with glutaraldehyde-polymerized allergen extract in adults and children.

Background: Allergies to fungi, such as , are significant contributors to respiratory conditions like asthma and rhinitis. Immunotherapy with native extracts often results in high rates of adverse reactions. This study evaluates the safety of immunotherapy using glutaraldehyde-polymerized extracts in both pediatric and adult populations.

The incidence of perioperative hypersensitivity reactions: a single-center, prospective, cohort study.

Background: The incidence of perioperative hypersensitivity reactions, which can be life-threatening, ranges from 1 in 20,000 to 1 in 1361. These reactions are usually classified as IgE or non-IgE mediated. The aim of this study was to determine the incidence of allergic reactions during general anesthesia in our hospital, to establish the incidence of the allergic reactions for each drug used, to assess the frequency of IgE-mediated reactions in even mild reactions, and to compare the degree of agreement between anesthesiologist suspicion and allergy diagnosis.