Publications by authors named "Grace Schulte"
Article Synopsis
- * Issues such as lot-to-lot variability and changes in stationary phase chemistry can affect the reliability of RPLC methods, leading to inconsistent results in practical applications.
- * The study investigated how the Hydrophobic Subtraction Model (HSM) could help explain variations in selectivity, particularly focusing on the selectivity differences between cis-trans isomers, revealing that the HSM may not fully account for these disparities.
The use of scanning gradients can significantly reduce method-development time in reversed-phase liquid chromatography. However, there is no consensus on how they can best be used. In the present work we set out to systematically investigate various factors and to formulate guidelines.
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