Epidemiological characteristics of the 2005 and 2007 dengue epidemics in Singapore - similarities and distinctions.

Introduction: We investigated the epidemiological features of the 2007 dengue outbreak to determine the factors that could have triggered it two years after the previous large outbreak in 2005.

Methods: All laboratory-confirmed cases of dengue reported during the year, as well as entomological and virological data, were analysed.

Results: A total of 8826 cases including 24 deaths were reported in 2007, giving an incidence of 192.

Early Dengue infection and outcome study (EDEN) - study design and preliminary findings.

Introduction: Dengue is a major public health problem in Singapore. Age-specific dengue morbidity rates are highest in the young adult population, unlike in many other Southeast Asian countries where dengue is mainly a paediatric disease. Hence, the World Health Organization (WHO) guidelines on dengue diagnosis and management which were developed using the paediatric experiences, may not be suitable for the management of adult dengue infections.