Publications by authors named "Grace M Weisman"
ACS Chem Neurosci
April 2024
Article Synopsis
- * The research aimed to combat neuroinflammation by targeting the NF-κB transcription factor and NLRP3 inflammasome protein using a new RNA-based treatment, SB_NI_112, which is safe and effectively penetrates the brain.
- * Treatment with SB_NI_112 in prion-diseased mice resulted in reduced inflammation, preserved neurons, improved cognitive function, and increased lifespan, suggesting potential for similar applications in other neurodegenerative diseases, despite limitations in the study.
