Osteoporosis is a major global health issue linked to weakened bones, prompting increased research into natural treatments, including various bark extracts.*
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This study assessed the antiosteoporosis effects and potential liver toxicity of these extracts by examining their impact on mouse bone cells and nitric oxide production in specific cell lines.*
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Results showed that the bark extracts significantly reduced harmful TRAP activity in bone cells and did not cause liver damage in zebrafish larvae, indicating potential for future osteoporosis drug development.*