Publications by authors named "Grace Hillmer"
Article Synopsis
- * This maturation process transforms initially immature virions into infectious particles by forming a fullerene core that contains genomic RNA and alters the surface distribution of the Env glycoprotein, which is vital for viral entry into host cells.
- * The article discusses host factors influencing maturation, the use of advanced microscopic technologies to study this process, and the development of antivirals targeting virion maturation for improved treatment options.
The maturation of HIV-1 virions is a crucial process in viral replication. Although T-cells are a primary source of virus production, much of our understanding of virion maturation comes from studies using the HEK293T human embryonic kidney cell line. Notably, there is a lack of comparative analyses between T-cells and HEK293T cells in terms of virion maturation efficiency in existing literature.
View Article and Find Full Text PDFThe maturation of HIV-1 virions is a crucial process in viral replication. Although T cells are a primary source of virus production, much of our understanding of virion maturation comes from studies using the HEK293T human embryonic kidney cell line. Notably, there is a lack of comparative analyses between T cells and HEK293T cells in terms of virion maturation efficiency in existing literature.
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