Publications by authors named "Grace H Holton"
Only 60-75% of conventional kidney stone surgeries achieve complete stone-free status. Up to 30% of patients with residual fragments <2 mm in size experience subsequent stone-related complications. Here we demonstrate a stone retrieval technology in which fragments are rendered magnetizable with a magnetic hydrogel so that they can be easily retrieved with a simple magnetic tool.
View Article and Find Full Text PDFArticle Synopsis
- People with kidney disease experience higher rates of atherosclerosis, and a protein called suPAR may play a key role in this connection.
- Research shows that higher suPAR levels can predict coronary artery calcification and cardiovascular events, with specific genetic variants linked to increased suPAR levels.
- In experiments, mice with elevated suPAR displayed more severe atherosclerosis due to heightened inflammation and changes in immune cell behavior, highlighting suPAR's potential as a target for understanding and treating atherosclerosis.