Publications by authors named "Grace Faulkner"
Article Synopsis
- Harmful algal blooms (HABs) have become more common worldwide, posing health risks due to various toxins, and poison control data helps track these exposures.
- This study analyzed 4,260 cyanoHAB exposure cases reported to U.S. poison control centers from 2010 to 2022, focusing on demographics, exposure circumstances, and health outcomes.
- Findings showed most affected individuals were young children, with exposures primarily occurring in public areas, and the overall incidence of cyanoHAB cases increased significantly over the study period, although severe outcomes were rare.
Harmful cyanobacteria (blue-green algae) exposures can cause illness or death in humans and animals. We characterized American Society for the Prevention of Cruelty to Animals (ASPCA) Animal Poison Control Center (APCC) harmful blue-green algae (HBGA) call data, compared it to a measure of harmful algal bloom public awareness, and considered its suitability as a public health information source. ASPCA APCC dog and cat "HBGA exposure" calls made 1 January 2010-31 December 2022 were included.
View Article and Find Full Text PDFDue to the central role of tubulin in various cellular functions, it is a validated target for anti-cancer therapeutics. However, many of the current tubulin inhibitors are derived from complex natural products and suffer from multidrug resistance, low solubility, toxicity issues, and/or the lack of multi-cancer efficacy. As such, there is a continued need for the discovery and development of new anti-tubulin drugs to enter the pipeline.
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