Publications by authors named "Grace E Geiger"

Hippocampal plasticity and memory are modulated by the potent estrogen 17β-estradiol (E). Research on the molecular mechanisms of hippocampal E signaling has uncovered multiple intracellular pathways that contribute to these effects, but few have questioned the role that extracellular signaling processes may play in E action. Modification of the extracellular matrix (ECM) by proteases like matrix metalloproteinase-9 (MMP-9) is critical for activity-dependent remodeling of synapses, and MMP-9 activity is required for hippocampal learning and memory.

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