[Autonomic nervous system dysfunction in Parkinson's disease evaluated by the heart rhythm variability test].

It is well recognized that autonomic dysfunction are common in Parkinson's disease (PD). Fourteen patients with early PD and 8 patients with advanced PD aged from 38-71 were investigated. Heart rate variability at rest differ significantly between patients with advanced PD and age-matched controls.

[The effect of some antioxidants on the response of selected lipid compounds in myocardium of rats].

Tests performed on 48 white rats were designed to evaluate the effect of such antioxidants as Allopurinol, Vitamin C, and Desferal on the lipid quantity in the rat heart muscle. The test animals were divided into control, Allopurinol, Vitamin C, and Desferal test groups in which free fatty acids, triglycerides, phospholipids, and total cholesterol were determined. It was observed that under the influence of Allopurinol and Vitamin C the heart muscle was bereaved of the essential energy compound, free fatty acids, to a large extent.

[The effect of antioxidants on lipid metabolism in myocardium in experimental hyperthyroxinemic conditions].

This experiment was conducted on 38 white Wistar-strain rats subdivided into five experimental groups. Group I were control animals which receiving intraperitoneal 0.5 ml injections of the sodium chloride physiological solution everyday during the whole experimental period of 26 days.

[Testing lipid metabolism in aortic walls of rats subjected to year-long cadmium intoxication].

The present work is continuation of experiments previously conducted on the impact of cadmium on the aortic lipid metabolism of rats. In the present experimental model, the duration of exposure to cadmium was increased four-fold: that is, to twelve months. The extension of the time of exposure was intended to make possible a more detailed analysis of aortic lipid metabolism.

[Evaluation of the toxic effects of cadmium on the body in light of research on the behavior of lipid compounds in aortic walls of animals].

The goal of this project was to observe certain paths of lipid metabolism in the aorta under the influence of chronic cadmium poisoning. A statistically very significant concentration of cadmium was found in the aortic walls of poisoned rats. However, the concentration of cadmium was not changed in the blood serum, where only a slight tendency towards increase was observed.

[Influence of chronic intoxication with cadmium chloride on the content of some lipids in lens and vitreous body of rabbits].

The experiments were carried out on 21 rabbits, divided into two groups. The first group consisted of 10 control animals, the second one consisted of 11 animals given per os 3 times per week for 3 months 1 ml of water solution of cadmium chloride in the dose of 0.35 mg for 1 kilogram of body weight.

[Influence of chronic poisoning with cadmium on some lipid compounds in heart muscle and aorta of rabbits].

The detection of the influence of chronic poisoning with cadmium on some lipid metabolism in heart muscle and aorta of rabbits was the main object of the paper. A distinct cumulation of cadmium in the heart muscle was observed. However, its excessive accumulation in the wall of the aorta was not noted.

[Effect of experimental diabetes and thyrotropic hormone on carbohydrate and lipid metabolism in heart and liver of rats].

The purpose of this research was to analyse the change in relationships between the carbohydrate and lipid metabolism parameters in the cardiac muscle and liver in the rats, in which the thyroid gland was induced additionally by use of thyrotropic hormone. The tests were performed on 33 white rats of the Wistar breed that were subdivided into four groups. The first group were reference animals.

[Initial investigations on the activity of some enzymes from the vitreous and lens of rabbit eyes exposed to cadmium and zinc].

The toxicological activity of zinc and cadmium is also connected with the negative influence of both compounds on the visual system. The activity of AspAT and AlAT was determined in 68 vitreous bodies and 68 lenses of rabbits exposed to the influence of zinc and cadmium compounds. Under the influence of these compounds the activity of AlAT was higher in the vitreous as well after using the cadmium or the zinc salts.

[Effect of diabetes and thyroid hypofunction on carbohydrate and lipid metabolism in heart and liver].

The purpose of this research was to analyse the change in relationships between the basic carbohydrate and lipid metabolisms parameters in the cardiac muscle and liver in the animals with diabetes, in which the thyroidal hypofunction was evoked additionally. The tests were performed on 43 white rats of the Wistar breed that were subdivided into four groups. The first group were reference animals.

[The effect of exertion on carbohydrate metabolism in myocardium of animals with experimental diabetes].

The aim of our experimental work was to investigate the carbohydrates metabolism in myocardium of experimental diabetic animals which were physically trained. The experiment was carried on a group of seventy white Wistar rats, which was divided into four subgroups. The first and the second subgroups consisted of normal animals.