Publications by authors named "Gozu Aydin"

Reconstruction of complex mid back wounds is challenging due to the patient comorbidities and scarcity of reliable regional flap alternatives. Four consecutive cases treated with perforator based V-Y advancement flaps are reported. An effective repair was achieved in all the patients and the mean follow up period was 28 months.

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  • The study investigated the effects of a synthetic somatostatin analogue, octreotide, on the delay of skin flap procedures in rats, comparing it to traditional surgical delay methods.
  • The research involved measuring gene expression and conducting histologic analysis at specific time intervals after preconditioning with octreotide.
  • Results indicated that while octreotide improved flap viability, it was less effective than surgical delay but could be a safe pharmacological alternative for enhancing flap survival.
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  • Neonates with Pierre Robin sequence experience airway obstruction and feeding issues due to a smaller jaw, with varying severity among patients.
  • In a study of 20 newborns, patients were categorized into three groups based on their condition, with most receiving non-surgical treatments like positioning and gavage feeding.
  • For those in the most severe group, surgical intervention (bilateral mandibular distraction) allowed successful breathing without needing a tracheostomy, though one patient had significant complications and another unfortunately passed away.
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Vascular malformations in the pediatric upper extremity remain a diagnostic and therapeutic challenge. Recent knowledge about diagnosis and treatment is provided including specific markers, imaging techniques, and management.

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  • The study aimed to assess how variations in the L-myc gene could indicate a genetic risk for head and neck nonmelanoma skin cancer (HNNMSC) and lower lip cancer (LLC).
  • Researchers conducted a case-control study involving 24 HNNMSC patients, 27 LLC patients, and 51 matched controls, using lab techniques to analyze gene variations.
  • Results showed a higher frequency of the LS genotype and S allele in cancer patients, suggesting that L-myc gene polymorphisms could aid in predicting cancer risk and tumor behavior, especially in those with HNNMSC.
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Amazia, the absence of the mammary gland, is a very rare congenital anomaly of the breasts. Bilateral absence of the breasts may occur as an isolated anomaly or may be associated with a syndrome or a cluster of other anomalies. Although the literature examining pediatric breast abnormalities is replete with case reports and series, bilateral amazia together with skeletal anomalies has not yet been described.

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Major surgical procedures can be performed safely for hemophiliacs provided the clotting factors are adequate. However, rhinoplasty, an elective facial procedure, has not yet been evaluated in this group of patients. The authors present a hemophilia A patient who underwent rhinoplasty for cosmetic reasons.

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Advances in reconstructive microsurgery have enabled us to make use of many flap alternatives in severe lower-extremity trauma, and traditional cross-leg flaps for wound coverage have been replaced in most centers by free-tissue transfers. But free-flap surgery is still a challenging area in very young pediatric populations because of technical difficulties with considerable drawbacks. Six children with severe foot and ankle trauma were presented.

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Botulinum exotoxin A has been used for the treatment of glabellar frown lines. Despite this fact, the effect of the toxin is sometimes either partial or lost in a short time. The muscles responsible for frowning, the corrugator supercilii and depressor supercilii muscles, are attached to the periosteum in the glabellar region under the frontalis muscle deep in the medial aspect.

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